Mebrosil

Mebrosil Uses, Dosage, Side Effects, Food Interaction and all others data.

Magnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.

Magnesium trisilicate works by increasing the pH of gastric juice via a neutralisation reaction. It also precipitates colloidal silica, which can coat gastrointestinal mucosa conferring further protection.

Trade Name Mebrosil
Generic Aluminium Hydroxide and Oxide + Magnesium Trisilicate
Weight 250mg, 500mg
Type Tablet
Therapeutic Class
Manufacturer Jawa Pharmaceuticals(pvt) Ltd,
Available Country Pakistan
Last Updated: September 19, 2023 at 7:00 am
Mebrosil
Mebrosil

Uses

Magnesium trisilicate is an antacid used for the symptomatic treatment of peptic ulcers.

For the treatment of peptic ulcers. Relieving indigestion and heartburn.

Mebrosil is also used to associated treatment for these conditions: Acid Reflux, Acid indigestion, Bloating, Colic, Flatulence, Gastric Ulcer, Heartburn, Upset stomach

How Mebrosil works

The gelatinous silicon dioxide, formed by the reaction of magnesium trisilicate with gastric contents is said to protect ulcerated mucosal surfaces and favor healing.

Toxicity

Adequate doses of magnesium trisilicate may cause diarrhea due to the action of soluble magnesium salts in the enteric tract. Approx 5% of the magnesium is absorbed.

Volume of Distribution

The hydrated silicon dioxide formed in the stomach and passes into the intestinal track.

Elimination Route

The hydrated silicon dioxide formed in the stomach and passes into the intestinal track where, silica can be partly absorbed.

Half Life

16-20 hours

Clearance

Maximum magnesium clearance is directly proportional to creatinine clearance.

Elimination Route

Excreted in the urine.

Innovators Monograph

You find simplified version here Mebrosil


*** Taking medicines without doctor's advice can cause long-term problems.
Share