Meclocyclinum

Meclocyclinum Uses, Dosage, Side Effects, Food Interaction and all others data.

Meclocyclinum is under investigation in clinical trial NCT00385515 (Efficacy of SNX-1012 in the Treatment of Oral Mucositis) .

Tetracyclines such as meclocycline are broad spectrum bacteriostatic agents . Meclocyclin likely inhibits the growth of bacterial species present in the damaged oral mucosa, allowing the immune system to more easily eliminate infections.

Meclocyclinum
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
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Interaction With other Medicine
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Trade Name	Meclocyclinum
Generic	Meclocycline
Meclocycline Other Names	Meclociclina, Meclocycline, Meclocyclinum
Type
Formula	C₂₂H₂₁ClN₂O₈
Weight	Average: 476.87 Monoisotopic: 476.0986433
Protein binding	Estimated plasma protein binding of ~75-91% based on that of demeclocycline due to structural similarity .
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Meclocyclinum is a tetracycline antibiotic indicated in the treatment of susceptible skin infections, bacterial vaginitis, vulvovaginitis, and cervicitis.

Currently under investigation for the topical treatment of ulcerative oral mucositis

Meclocyclinum is also used to associated treatment for these conditions: Bacterial Vaginitis, Cervicitis, Dermatitis, Secondary Infection, Skin Infections caused by tetracycline-sensitive bacteria, Vulvovaginitis

How Meclocyclinum works

As a tetracycline, meclocycline likely works by reversably associating with the 30s subint of the bacterial ribosome . A likely binding site for tetracyclines has been identified on protein S7 of this subunit. This association blocks the association of aminoacyl-tRNA with the ribosome, inhibiting protein synthesis. Ultimately this inhibits bacterial growth due to a lack of proteins necessary for reproduction.