Medrysone
Medrysone Uses, Dosage, Side Effects, Food Interaction and all others data.
Medrysone is a corticosteroid used in ophthalmology.
Medrysone is a topical anti-inflammatory corticoidsteroids for ophthalmic use. In patients with increased intraocular pressure and in those susceptible to a rise in intraocular pressure, there is less effect on pressure with medrysone than with dexamethasone or betamethasone. Corticoidsteroids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as well as capillary proliferation, deposition of collagen, and scar formation.
| Trade Name | Medrysone |
| Generic | Medrysone |
| Medrysone Other Names | Medrisona, Medrysone, Medrysonum |
| Weight | 1%w/v |
| Type | Eye Drops |
| Formula | C22H32O3 |
| Weight | Average: 344.4877 Monoisotopic: 344.23514489 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | Medipak Limited |
| Available Country | Pakistan |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Medrysone is a topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions.
For the treatment of allergic conjunctivitis, vernal conjunctivitis, episcleritis, and epinephrine sensitivity.
Medrysone is also used to associated treatment for these conditions: Conjunctivitis allergic, Conjunctivitis, Vernal, Epinephrine Sensitivity, Episcleritis
How Medrysone works
There is no generally accepted explanation for the mechanism of action of ocular corticosteroids. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Initially, the drug binds to the glucocorticoid receptor in the cytosol. This migrates to the nucleus and binds to genetic elements which cause activation and repression of the involved genes in the inflammatory pathway.
Food Interaction
No interactions found.Elimination Route
Rapidly absorbed following oral administration.
Innovators Monograph
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