Medrysone

Medrysone Uses, Dosage, Side Effects, Food Interaction and all others data.

Medrysone is a corticosteroid used in ophthalmology.

Medrysone is a topical anti-inflammatory corticoidsteroids for ophthalmic use. In patients with increased intraocular pressure and in those susceptible to a rise in intraocular pressure, there is less effect on pressure with medrysone than with dexamethasone or betamethasone. Corticoidsteroids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as well as capillary proliferation, deposition of collagen, and scar formation.

Trade Name Medrysone
Generic Medrysone
Medrysone Other Names Medrisona, Medrysone, Medrysonum
Weight 1%w/v
Type Eye Drops
Formula C22H32O3
Weight Average: 344.4877
Monoisotopic: 344.23514489
Groups Approved
Therapeutic Class
Manufacturer Medipak Limited
Available Country Pakistan
Last Updated: September 19, 2023 at 7:00 am
Medrysone
Medrysone

Uses

Medrysone is a topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions.

For the treatment of allergic conjunctivitis, vernal conjunctivitis, episcleritis, and epinephrine sensitivity.

Medrysone is also used to associated treatment for these conditions: Conjunctivitis allergic, Conjunctivitis, Vernal, Epinephrine Sensitivity, Episcleritis

How Medrysone works

There is no generally accepted explanation for the mechanism of action of ocular corticosteroids. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Initially, the drug binds to the glucocorticoid receptor in the cytosol. This migrates to the nucleus and binds to genetic elements which cause activation and repression of the involved genes in the inflammatory pathway.

Food Interaction

No interactions found.

Elimination Route

Rapidly absorbed following oral administration.

Innovators Monograph

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https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:34829
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http://www.genome.jp/dbget-bin/www_bget?drug:D02289
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https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=247839
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https://www.chemspider.com/Chemical-Structure.216968.html
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=29439
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=34829
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http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP001048
http://www.pharmgkb.org/drug/PA450346
http://www.rxlist.com/cgi/generic/medrysoneop.htm
https://www.drugs.com/mtm/medrysone-ophthalmic.html
https://en.wikipedia.org/wiki/Medrysone
*** Taking medicines without doctor's advice can cause long-term problems.
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