Megastene

Megastene Uses, Dosage, Side Effects, Food Interaction and all others data.

Megastene is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer. It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other thiamine derivatives. Although its clinical efficacy is not yet defined, sulbutiamine is used to treat asthenia. While its other uses include improvement of erectile dysfunction and reduction of psycho-behavioural inhibition, sulbutiamine showed evidence of modulatory effect on dopaminergic and glutamatergic cortical transmissions. The chronic administration of the drug has demonstrated to improve long term memory formation in mice.

Table Of contents

• Megastene
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Megastene
Generic	Sulbutiamine
Sulbutiamine Other Names	Sulbutiamina, Sulbutiamine
Type
Formula	C32H46N8O6S2
Weight	Average: 702.89 Monoisotopic: 702.298173581
Groups	Experimental
Therapeutic Class
Manufacturer
Available Country	Argentina
Last Updated:	September 19, 2023 at 7:00 am

Uses

Megastene is a thiamine derivative indicated in the treatment of asthenia.

Megastene is also used to associated treatment for these conditions: Loss of energy

Innovators Monograph

You find simplified version here Megastene