Melfil
Melfil Uses, Dosage, Side Effects, Food Interaction and all others data.
Avobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as wide spectrum sunscreens. Avobenzone is very sensitive to light, to increase its stability and duration of action, photostablizers are added in the sunscreen product. Avobenzone has an absorption maximum of 357 nm. Sunscreens containing avobenzone is indicated for providing protection from the sun. In addition to limiting the skin's exposure to the sun, using sunscreen agents may help reduce long-term sun damage such as premature aging of the skin and skin cancer.
Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin damage from prolonged sun exposure. Octocrylene is also often combined with avobenzone, another common sunscreen ingredient often appearing on ingredient labels. Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and skin care products, but the concentrations of this ingredient are usually limited to no more than 10 or 12 percent. However, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend to a variety of other products, like hair spray, tannin oil, BB cream, conditioner, and CC cream, among others. Octocrylene may cause contact and photocontact allergy.
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone.
Trade Name | Melfil |
Generic | Vitamin B3 / Nicotinic Acid / Niacin + Oxybenzone + Octocrylene + Octyl Methoxycinnamate + Magnesium Ascorbyl Phosphate + Vitamin E / Tocopherol + Avobenzone |
Weight | 1% |
Type | Cream |
Therapeutic Class | |
Manufacturer | Fourrts India Laboratories Pvt Ltd |
Available Country | India |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Avobenzone is a sunscreen agent found in sunscreens that absorbs UV rays.
Sun protection factor, added in the sunscreen products for its wide spectrum ultraviolet absorption properties.
Octocrylene is a sunscreen agent found in sunscreens that absorbs UV rays.
In the US, Octocrylene has been evaluated by the FDA and is considered safe for use up to 10% in the formula. Similarly, the EU allows its use up to 10% in a formula while Health Canada allows a maximum use level of 12%.
Oxybenzone is a sunscreen agent found in sunscreens that absorbs UV rays.
Used as an ingredient in sunscreen and other cosmetics.
Melfil is also used to associated treatment for these conditions: SunburnSunburnSunburn
How Melfil works
It blocks UVA I, UVA II, and UVB wavelengths, thereby limiting the impact of UV rays on skin. Diminish the penetration of ultraviolet (UV) light through the epidermis by absorbing UV radiation within a specific wavelength range. The amount and wavelength of UV radiation absorbed are affected by the molecular structure of the sunscreen agent.
Octocrylene is an effective oil soluble liquid UV‐B filter. It has excellent dissolving properties for crystalline UV filters. Due to its outstanding photostability it is used as photostabilizer. Conjugated acrylate portion absorbs UVB and short-wave UVA (ultraviolet) rays with wavelengths in the range of 280-320 nm which protects the skin from direct DNA damage. The ethylhexanol portion is a fatty alcohol, which functions as an emollient due to it's hydrophobicity.
Oxybenzone absorbs UV-A ultraviolet rays, preventing them from reaching the skin.
Toxicity
A minimum toxic dose has not been established. Significant toxicity is not expected
Octocrylene is one of those ingredients that can be absorbed into the skin and some studies have shown that it may promote generation of potentially harmful free radicals when exposed to light. Since free radicals can damage DNA, there is concern that this ingredient might have contributed to an increased incidence of melanoma in sunscreen-users compared to non-users.
Volume of Distribution
Ecamsule is only used topically, it not absorbed.
Elimination Route
Ecamsule is used topically, it not absorbed or metabolized.
Half Life
Ecamsule is only used topically, it does not have half life
Clearance
Ecamsule is used topically, it not absorbed or metabolized.
Elimination Route
Ecamsule is used topically, it not absorbed.
In vivo studies show oxybenzone is abosorbed transdermally (through the skin) and is excreted in the urine.
Innovators Monograph
You find simplified version here Melfil