Meline
Meline Uses, Dosage, Side Effects, Food Interaction and all others data.
Meline is an ethylenediamine derivative antihistamine with antimuscarinic and sedative properties.
| Trade Name | Meline |
| Generic | Mebhydrolin |
| Mebhydrolin Other Names | Mebhydrolin |
| Type | |
| Formula | C19H20N2 |
| Weight | Average: 276.383 Monoisotopic: 276.162648652 |
| Groups | Experimental |
| Therapeutic Class | Sedating Anti-histamine |
| Manufacturer | |
| Available Country | Taiwan |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Allergic disease or symptoms such as urticaria, pruritus of various origin, eczema, itching, drug rash, insect bites, allergic conjunctivitis, dermatitis of nutritional origin, hay fever, vasomotor rhinitis, allergic asthma.
Meline is also used to associated treatment for these conditions: Allergies
Dosage
Meline dosage
Adult: 100-300 mg/day or 2-6 tablets daily.
Child:
- 2-5 year: 50-150 mg/day or 1-3 tablets daily;
- 5-10 year: 100-200 mg/day or 2-4 tablets daily;
- >10 year: 100-300 mg/day or 2-6 tablets daily.
Treatment should be given in several single doses daily. Meline may be swallowed during or shortly after meals. For children, the tablet may be crushed and mixed with food.
Side Effects
Lassitude, dizziness, hypotension, muscular weakness, nausea, vomiting, diarrhoea or constipation, epigastric pain, headache, blurred vision, tinnitus, depression, nightmares, anorexia, dryness of the mouth, tightness of the chest, tingling, sedation, drowsiness etc. may occur.
Precaution
Closed-angle glaucoma; urinary retention, prostatic hyperplasia or pyloroduodenal obstruction; epilepsy. Elderly. Pregnancy. May impair ability to drive or operate machinery
Interaction
Enhanced sedation with alcohol or other CNS depressants. Additive antimuscarinic effects with MAOIs, atropine, TCAs. May mask warning symptoms caused by ototoxic agents e.g. aminoglycoside antibiotics.
Pregnancy & Breastfeeding use
Safety in pregnancy and lactation has not been established.
Contraindication
Hypersensitivity to any of the ingredients of Meline tablet or to mebhydrolin, prostatic hypertrophy, narrow-angle glaucoma, first trimester of pregnancy
Special Warning
Safety in pregnancy and lactation has not been established.
Storage Condition
Store below 25° C.
Innovators Monograph
You find simplified version here Meline
