Mephenesin
Mephenesin Uses, Dosage, Side Effects, Food Interaction and all others data.
Mephenesin is a synthetic cresol glyceryl ether which produces transient muscle relaxation and paralysis via central nervous system depression . It first entered use in the 1950s.
Mephenesin reduced neuronal excitability leading to decreases action potentials to muscle fibers which ultimately produces a reduction in spasticity .
| Trade Name | Mephenesin |
| Generic | Mephenesin |
| Mephenesin Other Names | Mephenesin |
| Type | |
| Formula | C10H14O3 |
| Weight | Average: 182.219 Monoisotopic: 182.094294311 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Mephenesin is a cresol glyceryl ether used to treat muscle spasticity in Parkinson's and Multiple Sclerosis.
Mephenesin was used for the treatment of muscle spasticity in diseases like Parkinson's or Multiple Sclerosis.
How Mephenesin works
The exact mechanism of action of mephenesin is not known. It has been observed to block both inward sodium and inward calcium currents in neurons . It has a physiological effect which opposes that of strychnine.
Toxicity
Mephenesin can produce hemolysis leading to hemoglobinuria with intravenous administration of concentrations greater than 10% . As a central nervous system depressant it can also produce paralysis and respiratory depression.
Innovators Monograph
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