Metalite Uses, Dosage, Side Effects and more
| Trade Name | Metalite |
| Availability | Prescription only |
| Generic | Trientine |
| Related Drugs | zinc acetate, penicillamine, Cuprimine, Syprine, Depen |
| Type | |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | Japan |
| Last Updated: | January 7, 2025 at 1:49 am |
Food Interaction
[Moderate] ADJUST DOSING INTERVAL: The gastrointestinal absorption of trientine may be decreased in the presence of food, resulting in reduced therapeutic effects.br>
MANAGEMENT: Metalite should be administered on an empty stomach, at least one hour before or two hours after meals and at least one hour apart from any other food, drug, or milk.
Metalite multivitamins interaction
[Moderate] GENERALLY AVOID: Concurrent oral administration of mineral supplements or mineral-containing products may block the absorption of trientine, and vice versa.
The mechanism is trientine chelation of polyvalent metal ions resulting in a nonabsorbable complex.
In general, mineral supplements or mineral-containing products (e.g., antacids) should not be used in patients treated with trientine.
If concomitant use is unavoidable, separation of administration times by at least two hours is advisable.
Metalite Drug Interaction
Unknown: diltiazem, diltiazem, ivabradine, ivabradine, penicillamine, penicillamine, acetaminophen / propoxyphene, acetaminophen / propoxyphene, phenoxybenzamine, phenoxybenzamine, antihemophilic factor, antihemophilic factor, immune globulin subcutaneous, immune globulin subcutaneous, pembrolizumab, pembrolizumab, methylphenidate, methylphenidate, sars-cov-2 , sars-cov-2
