Metenkefalin

Metenkefalin Uses, Dosage, Side Effects, Food Interaction and all others data.

Metenkefalin is an endogenous opioid and beta-endorphin. It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. Metenkefalin, along with tridecactide, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.

Trade Name Metenkefalin
Generic Metenkefalin
Metenkefalin Other Names Metenkefalin
Type
Formula C27H35N5O7S
Weight Average: 573.67
Monoisotopic: 573.225719661
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Metenkefalin
Metenkefalin

Uses

Metenkefalin is an investigational endogenous opioid being studied for the treatment of COVID-19.

Metenkefalin is indicated in Bosnia for the treatment of relapsing-remitting multiple sclerosis.

How Metenkefalin works

Metenkefalin is an agonist of µ and δ opioid receptors. It also causes immunostimulation at low doses and immunosuppression at higher doses. Metenkefalin can also inhibit the production of aldosterone, deoxycorticosterone, and corticosterone. Unfortuneately, the mechanisms by which these effects occur have not been well described in the literature.

Toxicity

Data regarding overdoses of metenkefalin are not readily available. Animal overdose studies have not determined an LD50.

Food Interaction

No interactions found.

Elimination Route

Metenkefalin reaches a Cmax of 1266.14pg/mL, with a Tmax of 0.16h, and an AUC of 360.64pg*h/mL.

Half Life

The half life of metenkefalin is 4.2-39 minutes.

Innovators Monograph

You find simplified version here Metenkefalin

*** Taking medicines without doctor's advice can cause long-term problems.
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