Methaqualone

Methaqualone Uses, Dosage, Side Effects, Food Interaction and all others data.

Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant. The sedative-hypnotic activity was first noted by Indian researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, sedative, and muscle relaxant commonly used for insomnia. It has also been used illegally as a recreational drug, commonly known as Quaaludes, Sopors, Ludes or Mandrax (particularly in the 1970s in North America) depending on the manufacturer. Since at least 2001, it has been widely used in South Africa, where it is commonly referred to as "smarties" or "geluk-tablette" (meaning happy tablets). Clandestinely produced methaqualone is still seized by government agencies and police forces around the world.

Trade Name Methaqualone
Generic Methaqualone
Methaqualone Other Names metacualona, Methaqualone
Type
Formula C16H14N2O
Weight Average: 250.2952
Monoisotopic: 250.11061308
Groups Illicit, Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Methaqualone
Methaqualone

Uses

For the treatment of insomnia, and as a sedative and muscle relaxant.

Toxicity

Symptoms of overdose include delirium, convulsions, muscle spasms or seizure, cardiac arrest, shortness or loss of breath, vomiting or nausea, and coma or death. The LD50 for mice is 1250 mg/kg and for rats is 326 mg/kg (Strasenburg Labs).

Innovators Monograph

You find simplified version here Methaqualone

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0000002
http://classyfire.wishartlab.com/tax_nodes/C0004788
http://classyfire.wishartlab.com/tax_nodes/C0004789
http://classyfire.wishartlab.com/tax_nodes/C0000485
http://classyfire.wishartlab.com/tax_nodes/C0001091
http://classyfire.wishartlab.com/tax_nodes/C0000291
http://classyfire.wishartlab.com/tax_nodes/C0004144
http://classyfire.wishartlab.com/tax_nodes/C0000160
http://classyfire.wishartlab.com/tax_nodes/C0004139
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0000323
http://classyfire.wishartlab.com/tax_nodes/C0000278
http://classyfire.wishartlab.com/tax_nodes/C0003940
http://classyfire.wishartlab.com/tax_nodes/C0004150
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:6821
http://www.hmdb.ca/metabolites/HMDB0240285
http://www.genome.jp/dbget-bin/www_bget?drug:D00557
http://www.genome.jp/dbget-bin/www_bget?cpd:C07560
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=6292
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46507178
https://www.chemspider.com/Chemical-Structure.6055.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50089081
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=6823
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=6821
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL282052
https://zinc.docking.org/substances/ZINC000002568176
https://en.wikipedia.org/wiki/Methaqualone
*** Taking medicines without doctor's advice can cause long-term problems.
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