Methyvit
Methyvit Uses, Dosage, Side Effects, Food Interaction and all others data.
A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Kaolin is a layered silicate mineral. Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics. Until the early 1990s it was the active substance of anti-diarrhoea medicine Kaopectate.
Kaolin is an adsorptive agent.
Trade Name | Methyvit |
Generic | Furazolidone + Kaolin + Pectin +Mecobalamin |
Weight | 0, 500mcg/ml |
Type | Tablet, Injection |
Therapeutic Class | |
Manufacturer | Danas Pharmaceuticals (pvt) Ltd |
Available Country | Pakistan |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Furazolidone is a drug for the treatment of infectious diarrhea.
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Kaolin is a natural ingredient used for the short-term symptomatic treatment of various conditions including diarrhea, skin dryness, and minor skin bleeding.
Used for upset stomach and diarrhea, a traditional medicine used in China, South America and Africa. Kaolin is also used to treat AIDs-related diarrhea. Kaolin based bandages are also under investigation.
Methyvit is also used to associated treatment for these conditions: Dysentery, Infectious diarrheaDiaper Rash, Diarrhoea, Dysentery, Enteritis infectious, Gastric Ulcer, Loose bowel movements, Stomach pains caused by Gastric Acid
How Methyvit works
Furazolidone and its related free radical products are believed to bind DNA and induce cross-links. Bacterial DNA is particularly susceptible to this drug leading to high levels of mutations (transitions and transversions) in the bacterial chromosome.
Kaolin adsorbs water, toxins and bacteria, contributing to firmer stools, reducing fluid loss from diarrhea.
Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Elimination Route
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Half Life
10 minutes
Innovators Monograph
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