Metrodiol

Metrodiol Uses, Dosage, Side Effects, Food Interaction and all others data.

A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been marketed, see Etynodiol).

Ethynodiol Diacetate is used as a female contraceptive. Ethynodiol Diacetate is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Ethynodiol Diacetate tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries.

Trade Name Metrodiol
Generic Ethynodiol diacetate
Ethynodiol diacetate Other Names Ethynodiol diacetate, Etynodiol acetate, Etynodiol diacetate
Type
Formula C24H32O4
Weight Average: 384.5085
Monoisotopic: 384.230059512
Protein binding

50-85%

Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Metrodiol
Metrodiol

Uses

Metrodiol is an oral contraceptive used to prevent pregnancy.

For the prevention of pregnancy in women who elect to use this product as a method of contraception.

Metrodiol is also used to associated treatment for these conditions: Abnormal Uterine Bleeding, Hypermenorrhea, Menstrual Distress (Dysmenorrhea), Pain, Polycystic Ovarian Syndrome, Oral Contraceptives

How Metrodiol works

Binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like Ethynodiol Diacetate will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.

Food Interaction

No interactions found.

Innovators Monograph

You find simplified version here Metrodiol

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0000012
http://classyfire.wishartlab.com/tax_nodes/C0000258
http://classyfire.wishartlab.com/tax_nodes/C0001691
http://classyfire.wishartlab.com/tax_nodes/C0001691
http://classyfire.wishartlab.com/tax_nodes/C0001466
http://classyfire.wishartlab.com/tax_nodes/C0002978
http://classyfire.wishartlab.com/tax_nodes/C0001373
http://classyfire.wishartlab.com/tax_nodes/C0000346
http://classyfire.wishartlab.com/tax_nodes/C0001238
http://classyfire.wishartlab.com/tax_nodes/C0004478
http://classyfire.wishartlab.com/tax_nodes/C0003940
http://classyfire.wishartlab.com/tax_nodes/C0004150
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:31580
http://www.genome.jp/dbget-bin/www_bget?cpd:C12724
http://www.lipidmaps.org/data/LMSDRecord.php?LMID=LMST02030124
http://www.hmdb.ca/metabolites/HMDB0014961
http://www.genome.jp/dbget-bin/www_bget?drug:D01294
http://www.genome.jp/dbget-bin/www_bget?cpd:C12724
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=9270
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46506993
https://www.chemspider.com/Chemical-Structure.8913.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237627
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=4170
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=31580
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL1200624
https://zinc.docking.org/substances/ZINC000003876023
http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000856
http://www.pharmgkb.org/drug/PA164749157
http://www.rxlist.com/cgi/generic/ethynoc.htm
https://en.wikipedia.org/wiki/Etynodiol_diacetate
*** Taking medicines without doctor's advice can cause long-term problems.
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