Miansan

Miansan Uses, Dosage, Side Effects, Food Interaction and all others data.

A tetracyclic compound with antidepressant effects. Miansan was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.

Miansan is a tetracyclic antidepressant that has antihistaminic and hypnosedative, but almost no anticholinergic, effect. It is a weak inhibitor of norepinephrine reuptake and strongly stimulates the release of norepinephrine. Interactions with serotonin receptors in the central nervous system have also been found. Its effect is usually noticeable after one to three weeks. Miansan may cause drowsiness and hematological problems.

Trade Name Miansan
Generic Mianserin
Mianserin Other Names Mianserin, Mianserina, Mianserine, Miansérine, Mianserinum, Mianseryna
Type
Formula C18H20N2
Weight Average: 264.3648
Monoisotopic: 264.16264865
Protein binding

90%

Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country Russia
Last Updated: September 19, 2023 at 7:00 am
Miansan
Miansan

Uses

Miansan is a tetracyclic antidepressant with therapeutic activity similar to amitriptyline used to treat depression and anxiety.

For the treatment of depression.

Miansan is also used to associated treatment for these conditions: Depression

How Miansan works

Miansan's mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.

Toxicity

Oral rat LD50: 780mg/kg

Elimination Route

Absorbed following oral administration.

Half Life

10-17 hours

Innovators Monograph

You find simplified version here Miansan

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0000002
http://classyfire.wishartlab.com/tax_nodes/C0000293
http://classyfire.wishartlab.com/tax_nodes/C0000320
http://classyfire.wishartlab.com/tax_nodes/C0000320
http://classyfire.wishartlab.com/tax_nodes/C0002000
http://classyfire.wishartlab.com/tax_nodes/C0003901
http://classyfire.wishartlab.com/tax_nodes/C0003358
http://classyfire.wishartlab.com/tax_nodes/C0000069
http://classyfire.wishartlab.com/tax_nodes/C0003899
http://classyfire.wishartlab.com/tax_nodes/C0002448
http://classyfire.wishartlab.com/tax_nodes/C0002239
http://classyfire.wishartlab.com/tax_nodes/C0004139
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0004150
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:51137
http://www.hmdb.ca/metabolites/HMDB0015620
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=4184
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508096
https://www.chemspider.com/Chemical-Structure.4040.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222218
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=6929
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=51137
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL6437
http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000293
http://www.pharmgkb.org/drug/PA134687937
http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=135
https://en.wikipedia.org/wiki/Mianserin
*** Taking medicines without doctor's advice can cause long-term problems.
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