Mircol

Mircol Uses, Dosage, Side Effects, Food Interaction and all others data.

Mircol is a histamine H1 antagonist (antihistamine). It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Mircol is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Trade Name Mircol
Generic Mequitazine
Mequitazine Other Names Mequitazina, Mequitazine, Mequitazinum
Type
Formula C20H22N2S
Weight Average: 322.467
Monoisotopic: 322.150369404
Groups Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Mircol
Mircol

Uses

For the treatment of Hay fever, urticaria (hives) and allergic rhinitis

How Mircol works

Mircol binds to the histamine H1 receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.

Innovators Monograph

You find simplified version here Mircol

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0000002
http://classyfire.wishartlab.com/tax_nodes/C0000309
http://classyfire.wishartlab.com/tax_nodes/C0000310
http://classyfire.wishartlab.com/tax_nodes/C0000310
http://classyfire.wishartlab.com/tax_nodes/C0003902
http://classyfire.wishartlab.com/tax_nodes/C0003864
http://classyfire.wishartlab.com/tax_nodes/C0000252
http://classyfire.wishartlab.com/tax_nodes/C0000195
http://classyfire.wishartlab.com/tax_nodes/C0002448
http://classyfire.wishartlab.com/tax_nodes/C0001349
http://classyfire.wishartlab.com/tax_nodes/C0002239
http://classyfire.wishartlab.com/tax_nodes/C0004139
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0004150
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:31821
http://www.hmdb.ca/metabolites/HMDB0015204
http://www.genome.jp/dbget-bin/www_bget?drug:D01324
http://www.genome.jp/dbget-bin/www_bget?cpd:C12755
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=4066
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46505779
https://www.chemspider.com/Chemical-Structure.3926.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=430669
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=29528
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=31821
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL73451
http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP001078
http://www.pharmgkb.org/drug/PA164748010
https://en.wikipedia.org/wiki/Mequitazine
*** Taking medicines without doctor's advice can cause long-term problems.
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