MRx-4DP0004

MRx-4DP0004 Uses, Dosage, Side Effects, Food Interaction and all others data.

MRx-4DP0004 is a lyophilised formulation of the Bifidobacterium breve strain of commensal bacteria. It is a live biotherapeutic derived from the microbiota of a healthy human infant.

Trade Name MRx-4DP0004
Generic MRx-4DP0004
Type
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
MRx-4DP0004
MRx-4DP0004

Uses

MRx-4DP0004 is a probiotic bacteria indicated in the treatment of diarrhea.

How MRx-4DP0004 works

MRx-4DP0004 is an immunomodulatory therapy with anti-viral activity that simultaneously downregulates molecules associated with hyper-inflammatory responses. It reduces neutrophilic and eosinophilic infiltration in the lungs, in addition to a reduction in peribronchiolar and perivascular immunopathology without the side effects associated with immunosuppressants. A study of MRx-4DP0004 also demonstrated specifics of the biotherapeutic increasing lung D4+CD44+ cells and CD4+FoxP3+ cells, decreasing activated CD11b+ dendritic cells, and reducing pro-inflammatory cytokines and chemokines involved in neutrophil migration. MRx-4DP0004 is currently being investigated for severe asthma management, however, the specific mechanism of action is currently unknown.

Innovators Monograph

You find simplified version here MRx-4DP0004


*** Taking medicines without doctor's advice can cause long-term problems.
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