Multibrim
Multibrim Uses, Dosage, Side Effects, Food Interaction and all others data.
Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.
Trade Name | Multibrim |
Generic | Vitamin B1 / Thiamine + Vitamin E / Tocopherol + Vitamin B2 / Riboflavin + Vitamin A / Retinol + Magnesium Oxide + Vitamin C / Ascorbic Acid + Vitamin D3 / Cholecalciferol + Mecobalamin + Vitamin B6 / Pyridoxine |
Weight | 10mg |
Type | Tablet |
Therapeutic Class | |
Manufacturer | Brzee Medscience |
Available Country | India |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Magnesium oxide is a compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and neuromuscular health.
Indicated for over-the-counter use as a supplement for cardiovascular and neuromuscular health, and as an antacid for relief of acid indigestion and upset stomach.
Mecobalamin is used for-
- Peripheral Neuropathies
- Diabetic Neuropathy
- Verteberal Syndrome
- Nerve Compression Syndrome
- Multiple sclerosis
- Amyotrophic lateral sclerosis
- Parkinson’s disease
- Alzheimer’s disease
- Diabetic retinopathy
- Entrapment neuropathy
- Drug induced neuropathy
- Megaloblastic anemia due to Vitamin B12 deficiency
Multibrim is also used to associated treatment for these conditions: Acid indigestion, Heartburn, Bowel preparation therapy, Nutritional supplementationVitamin B12 Deficiency, Nutritional supplementation
How Multibrim works
The term "Milk of Magnesia" was first used to describe a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestion and heartburn. When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend the bowel, thus stimulating nerves within the colon wall, inducing peristalsis and resulting in evacuation of colonic contents. Magnesium supplements have also been shown to reduce platelet aggregation by inhibiting in the influx of calcium, a crucial component of platelet aggregation.
Dosage
Multibrim dosage
Tablet: The usual adult dosage is one 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms.
Injection:
- Peripheral neuropathies: The usual adult dosage is one ampoule equivalent to 500 mcg of Mecobalamin, administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.
- Megaloblastic anemia: The usual adult dosage is one ampoule equivalent to 500 mcg of Mecobalamin, administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Mecobalamin every one to three months as maintenance therapy
Side Effects
Generally Mecobalamin is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of Mecobalamin.
Precaution
The medicine should not be used for months if there is no response at all after its use for a certain period of time.
Interaction
Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.
Pregnancy & Breastfeeding use
Not recommended during pregnancy & lactation.
Contraindication
Hypersensitivity to any component of this product.
Special Warning
Use in children: Not recommended.
Storage Condition
Oral: Store at room temperature. Protect from moisture and light.
Parenteral: Store at room temperature. Do not expose to direct light.
Innovators Monograph
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