N-dimethylserotonin
N-dimethylserotonin Uses, Dosage, Side Effects, Food Interaction and all others data.
A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.
Bufotenin is a tryptamine related to the neurotransmitter serotonin.
| Trade Name | N-dimethylserotonin |
| Generic | Bufotenine |
| Bufotenine Other Names | Bufotenin, DM5-HT, N,N-dimethylserotonin |
| Type | |
| Formula | C12H16N2O |
| Weight | Average: 204.2682 Monoisotopic: 204.126263144 |
| Groups | Experimental, Illicit |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Toxicity
Ingestion of Bufo toad venom and eggs by humans has resulted in several reported cases of poisoning, some of which resulted in death. The acute toxicity of bufotenin in rodents has been calculated to have an LD50 of between 200 and 300 mg/kg, which by comparison, is comparable to the LD50 for intravenous morphine (200-300 mg/kg) in mice. Respiratory arrest may occur, possibly leading to death.
Elimination Route
Rapidly absorbed following intravenous administration.
Innovators Monograph
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