Natfol Tablet 5 mg Uses, Dosage, Side Effects and more
Natfol Tablet 5 mg Uses, Dosage, Side Effects, Food Interaction and all others data.
Trade Name | Natfol Tablet 5 mg |
Generic | Calcium Folinate [Folinic Acid] |
Weight | 5 mg |
Type | Tablet |
Therapeutic Class | Supportive Care Therapy |
Manufacturer | Somatec Pharmaceuticals Ltd. |
Available Country | Bangladesh |
Last Updated: | January 7, 2025 at 1:49 am |
Uses
Calcium Folinate is indicated in: To diminish the toxicity and counteract the effect of impaired Methotrexate elimination. To treat the Megaloblastic anemia due to folate deficiency, as in sprue, nutritional deficiency. To treat the Megaloblastic anemia of pregnancy and infancy.Dosage
Natfol Tablet 5 mg dosage
Oral- Reduction of harmful effects of folic acid antagonists such as Methotrexate, Trimethoprim etc: The dose is usually one 5-15mg tablet every 6 hours for 2 to 3 days. Megaloblastic anemia: In the treatment of Megaloblastic anemia, the dose is one 5-15 mg tablet daily. Or, as directed by the registered physician. Intravenous- Advanced Colorectal Cancer: Leucovorin is administered at 200 mg/m2 by slow intravenous injection followed by 5-fluorouracil at 370 mg/m2 by intravenous injection. Or 20 mg/m 2 by slow intravenous injection followed by 5-fluorouracil at 425 mg/m2 by intravenous injection. Treatment is repeated daily for 5 days. This 5 day treatment course may be repeated at 4 weeks interval, for 2 courses and then may repeated at 4-5 weekly intervals if the patient has recovered completely from the toxic effects of the prior treatment course. Folinic acid rescue after high dose Methotrexate Therapy: Leucovorin starts 24 hours after the beginning of the methotrexate infusion at dose of 15mg (10 mg/m2 ) every 6 hours for 10 doses. Intramuscular- Folate deficient megaloboastic anaemia: Up to 1 mg/day. Or, as directed by the registered physician.