Naturlose
Naturlose Uses, Dosage, Side Effects, Food Interaction and all others data.
Naturlose is a functional sweetener. It is a naturally occurring monosaccharide, specifically a hexose. It is commonly found in dairy with a similar texture and sweetened capacity to sucrose but with only a third of the calories. It is approved as a food additive as a low calorie sweetener. Additionally, it is under investigation by Spherix for the treatment of obesity and type II diabetes.
Oral tagatose significantly blunts the rise in plasma glucose seen after oral glucose in patients with diabetes mellitus in a dose-dependent manner without significantly affecting insulin levels. The minimal elevation of plasma tagatose levels in normal patients and the adverse gastrointestinal effects seen following larger doses of tagatose support poor absorption of this hexose and suggest that tagatose may act by attenuating glucose absorption in the intestine.
| Trade Name | Naturlose |
| Generic | Tagatose |
| Tagatose Other Names | D-lyxo-hexulose, D-tag, D-tagatose, keto-D-tagatose |
| Type | |
| Formula | C6H12O6 |
| Weight | Average: 180.1559 Monoisotopic: 180.063388116 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Intended for use as a therapeutic adjunct in the treatment of type II diabetes.
How Naturlose works
he steps in the metabolism of tagatose are identical to those for fructose or fruit sugar but tagatose is incompletely absorbed. Only 15-20 percent of tagatose is absorbed in the small intestine. The major part of ingested tagatose is fermented in the colon by indigenous microflora, resulting in the production of short-chain fatty acids. The short chain fatty acids are absorbed almost completely and metabolized.
Elimination Route
Only 15-20 percent of tagatose is absorbed in the small intestine.
Innovators Monograph
You find simplified version here Naturlose
