NCX 1022 Uses, Dosage, Side Effects and more
NCX is an NO-releasing derivative of hydrocortisone.
Trade Name | NCX 1022 |
Generic | NCX 1022 |
Type | |
Formula | C29H35NO9 |
Weight | Average: 541.597 Monoisotopic: 541.231181711 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in atopic dermatitis.
How NCX 1022 works
NCX 1022 is designed to have potent anti- inflammatory activity combined with a significantly improved safety and tolerability profile, in particular the absence of skin blanching after repeated use.It is better than hydrocortisone in terms of inhibiting benzalkonium chloride-induced leukocyte adhesion to the endothelium, without affecting the flux of rolling leukocytes or venule diameter.