Neo Ultraxon
Neo Ultraxon Uses, Dosage, Side Effects, Food Interaction and all others data.
Neo Ultraxon is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Neo Ultraxon was first introduced as an anthelmintic in 1953. Neo Ultraxon compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.
Neo Ultraxon is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Neo Ultraxon hydrate and piperazine citrate are the main anthelminthic piperazines.
| Trade Name | Neo Ultraxon |
| Availability | Discontinued |
| Generic | Piperazine |
| Piperazine Other Names | Diethylenediamine, Piperazidine, Piperazin, Piperazina, Piperazine |
| Related Drugs | albendazole, mebendazole, nitazoxanide, pyrantel, Albenza, Alinia, Emverm, Ascarel |
| Weight | 1g/5ml |
| Type | Syrup |
| Formula | C4H10N2 |
| Weight | Average: 86.1356 Monoisotopic: 86.08439833 |
| Protein binding | 60-70% |
| Groups | Approved, Vet approved |
| Therapeutic Class | |
| Manufacturer | Henson Farma |
| Available Country | Indonesia |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Neo Ultraxon is a medication used to treat roundworm and pinworm.
Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.
Neo Ultraxon is also used to associated treatment for these conditions: Ascaris lumbricoides infection, Enterobius vermicularis infection
How Neo Ultraxon works
Neo Ultraxon is a GABA receptor agonist. Piperzine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.
Toxicity
LD50 = 5 g/kg (Human, oral). Symptoms of overdose include muscle fatigue, seizures, and difficulty breathing.
Food Interaction
- Take with or without food. The absorption is unaffected by food.
Neo Ultraxon Disease Interaction
Major: liver disease, renal dysfunctionModerate: supportive therapy, seizure disorders
Elimination Route
Rapidly absorbed from the gastrointestinal tract
Innovators Monograph
You find simplified version here Neo Ultraxon
