Neohetramine
Neohetramine Uses, Dosage, Side Effects, Food Interaction and all others data.
Neohetramine is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
Neohetramine is a first-generation antihistamine. It antagonizes the action of histamine to relief allergic symptoms like nasal congestion, runny nose, itchy eyes, itchy nose and throat, and sneezing
| Trade Name | Neohetramine |
| Generic | Thonzylamine |
| Thonzylamine Other Names | neohetramine, Thonzylamine |
| Type | |
| Formula | C16H22N4O |
| Weight | Average: 286.379 Monoisotopic: 286.179361344 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Thozylamine is indicated for use in the symptomatic control of allergic rhinitis or other upper respiratory allergic symptoms . It is typically a part of combination over the counter products.
Neohetramine is also used to associated treatment for these conditions: Allergies, Cough, Nasal Congestion, Ocular Infections, Irritations and Inflammations, Ocular Irritation
How Neohetramine works
Neohetramine competes with histamine for binding to the H1 histamine receptor . Binding of histamine to this receptor stimulates vasodilation and increased vascular permeability leading to nasal congestion and runny nose . Histamine also produces itchiness by stimulating nerve endings which can result in sneezing. By blocking these effects, thonzylamine can reduce or eliminate symptoms of allergic rhinitis.
Toxicity
Doses of up to 300 mg/day for up to 4 days have produces no observable toxic effects in humans . In a chronic toxicity study, rats were given up to 200 mg/kg/day orally for 91 days with no observable toxic effects .
Food Interaction
No interactions found.Innovators Monograph
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