Nikethamide-Eskom

Nikethamide-Eskom Uses, Dosage, Side Effects, Food Interaction and all others data.

Nikethamide-Eskom was formerly used as a respiratory stimulant but its use for this indication is no longer recommended as the effective doses are close to those causing toxic effects (especially convulsions).

Nikethamide-Eskom
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Nikethamide-Eskom
Generic	Nikethamide
Nikethamide Other Names	Nikethamide
Type
Formula	C₁₀H₁₄N₂O
Weight	Average: 178.235 Monoisotopic: 178.110613079
Groups	Experimental
Therapeutic Class	Respiratory stimulants: analeptics
Manufacturer
Available Country	Russia
Last Updated:	September 19, 2023 at 7:00 am

Uses

Central respiratory depression, Energy malnutrition, Tranquilizer overdoses

Nikethamide-Eskom is also used to associated treatment for these conditions: Respiratory stimulation

Dosage

Nikethamide-Eskom dosage

1500 mg as single dose

Side Effects

Dyspnoea, respiratory problems; muscular, GI, CNS and CV effects. Convulsions.

Precaution

Less severe degrees of hypertension or impaired cardiac reserve; liver dysfunction.

Interaction

Additive pressor effects with sympathomimetics or MAOIs. Increased risk of cardiac arrythmias with some anaesthetics (halothane, enflurane, isoflurane). May mask the effects of neuromuscular blockers. Increased risk of convulsions with bupropion.

Pregnancy & Breastfeeding use

Pregnancy category- Not classified

Contraindication

Porphyria, epilepsy or other convulsive disorders, cerebral oedema, cerebrovascular accident, head injury, acute severe asthma, physical obstruction of the airway, severe hypertension, ischaemic heart disease, hyperthyroidism, phaeochromocytoma.