Nipheal
Nipheal Uses, Dosage, Side Effects, Food Interaction and all others data.
Nipheal is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments .
Nipheal is the purified, secreted product of the sheep sebaceous glands . Nipheal primarily consists of long-chain waxy esters, or sterol esters, that lack glycerides. For this reason, it is also called wool wax or wool grease. Nipheal is used in the protection, treatment, and cosmetic enhancement of human skin. Its hydrophobic properties can help protect skin against infections or skin irritation, as it helps seal in moisture that is already present in the skin .
Nipheal is used as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and facial cosmetics. Nipheal is also frequently used in protective baby skin treatment and for sore nipples in breastfeeding mothers , .
| Trade Name | Nipheal |
| Availability | Rx and/or OTC |
| Generic | Lanolin |
| Lanolin Other Names | Fats, lanolin, Lanolin, Lanolin oil, Wool fat, Wool grease, Wool oil, Wool wax, lanolin, Wool wax, refined |
| Related Drugs | Calmoseptine, zinc oxide topical, dimethicone topical, AmLactin, ammonium lactate topical, urea topical, Desitin Rapid Relief Cream |
| Weight | 0.2% |
| Type | Cream |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | Novartis India Ltd |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Nipheal is an ingredient used in skin care products to relieve irritation.
Used as a skin protectant, and to relieve dryness and irritation of the skin , . Helps prevent and treat diaper dermatitis .
Nipheal is also used to associated treatment for these conditions: Eye lubrication, Skin protection
How Nipheal works
Nipheal is an emollient. Emollients soften the skin by forming an occlusive oil film on the stratum corneum layer of the epithelium, thus decreasing the transepidermal water loss .
Toxicity
Studies have shown a positive association between atopic dermatitis and lanolin contact allergy . The prevalence of lanolin allergy is low (1.8%-2.5%) . Patch testing with lanolin is helpful in patients with dermatitis and suspected cosmetic allergy .
The acute dermal LD50 of lanolin oil was > 10 mL/kg for rabbits .
Food Interaction
No interactions found.Innovators Monograph
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