Norzy D

Norzy D Uses, Dosage, Side Effects, Food Interaction and all others data.

A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.

Norfloxacin is a quinolone/fluoroquinolone antibiotic. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Notably the drug has 100 times higher affinity for bacterial DNA gyrase than for mammalian.

Trade Name Norzy D
Generic Dexamathasone + Norfloxacin
Type Eyeear Drops
Therapeutic Class
Manufacturer Zee Laboratories Ltd
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Norzy D
Norzy D

Uses

Norfloxacin is a broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine.

For the treatment of urinary tract infection

Norzy D is also used to associated treatment for these conditions: Cystitis, Gonococcal cervicitis, Infectious diarrhea, Pyelitis, Pyelonephritis, Spontaneous Bacterial Peritonitis (SBP), Traveler's Diarrhea, Urethritis gonococcal

How Norzy D works

The bactericidal action of Norfloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, and recombination. Norfloxacin is a broad-spectrum antibiotic agent that is shown to be effective against various Gram-positive and Gram-negative bacterial species. The fluorine atom at the 6 position increases potency against gram-negative organisms, and the piperazine moiety at the 7 position is responsible for anti-pseudomonal activity

Elimination Route

Rapid

Half Life

3-4 hours

Elimination Route

Norfloxacin is eliminated through metabolism, biliary excretion, and renal excretion. It is expected to undergo both glomerular filtration and tubular secretion during renal excretion, as shown by its high renal clearance rate of approximately 275 mL/min.

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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