Nuquin HP
Nuquin HP Uses, Dosage, Side Effects, Food Interaction and all others data.
Nuquin HP is a topical depigmentating agent that produces a reversible depigmentation of the skin by inhibiting enzymatic oxidation of tyrosine to 3,4-dihydroxyphenylalanine and suppressing melanocyte metabolic processes.
| Trade Name | Nuquin HP |
| Generic | Hydroquinone |
| Hydroquinone Other Names | 1,4-benzenediol, Hydroquinone, Quinol |
| Weight | 2%, 4%, 6%, 8%, |
| Type | Cream, Gel, Topical Cream, Topical Emulsion, Topical Gel |
| Formula | C6H6O2 |
| Weight | Average: 110.1106 Monoisotopic: 110.036779436 |
| Groups | Approved, Investigational |
| Therapeutic Class | Hydroquinone Preparations |
| Manufacturer | |
| Available Country | United States |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Nuquin HP is used -
- For the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other unwanted areas of melanin hyperpigmentation.
- To reduce hyperpigmentation caused by photosensitization associated with inflammation or with the use of certain cosmetics.
Nuquin HP is also used to associated treatment for these conditions: Acne Vulgaris, Melasma, Skin hyperpigmentation, Moderate Melasma, Severe Melasma
How Nuquin HP works
Nuquin HP reduces melanin pigment production through inhibition of the tyrosinase enzyme, which is involved in the initial step of the melanin pigment biosynthesis pathway. Nuquin HP takes several months to take effect.
Dosage
Nuquin HP dosage
Apply a thin film of Nuquin HP Cream to the effected area once daily, at least 30 minutes before bedtime. Gently wash the face and neck with a mild cleanser. Rinse and pat the skin dry. Apply Nuquin HP Cream to the hyperpigmented areas of melasma including about ½ inch of normal appearing skin surrounding eachlesion. Rub lightly and uniformly into the skin.
Therapy should be discontinued when control is achieved. During the day, use asunscreenof SPF 30, and wear protective clothing. Avoid sunlight exposure. Patients may use moisturizers and/or cosmetics during the day. Nuquin HP Cream is for topical use only. It is not for oral,ophthalmic, or intravaginal use.
Side Effects
No systemic adverse reactions have been reported. Occasional hypersensitivity (localized contact dermatitis) may occur in which case the medication should be discontinued.
Precaution
Nuquin HP is a skin bleaching agent which may produce unwanted cosmetic effects if not used as directed. The physician should be familiar with the contents of this insert before prescribing or dispensing this medication.
Test for skin sensitivity before using by applying a small amount to an unbroken patch of skin to check in 24 hours. Minor redness is not a contraindication, but where there is itching or vesicle formation or excessive inflammatory response, further treatment is not advised. If no bleaching or lightening effect is noted after 2 months of treatment, the medication should be discontinued.
Contact with the eyes and lips should be avoided. Nuquin HP should not be applied to cut or abraded skin.
Food Interaction
No interactions found.Pregnancy & Breastfeeding use
Pregnancy Category C. Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Lactation: It is not known whether topical hydroquinone is absorbed or excreted in human milk. Caution is advised when topical hydroquinone is used by a nursing mother.
Contraindication
Nuquin HP is contraindicated to patients with prior history of hypersensitivity or allergic reaction to hydroquinone or other ingredients in the preparation.
Acute Overdose
There have been no systemic reactions from the use of topical hydroquinone. Some patients may experience a transient reddening of skin and mild burning sensation which does not preclude treatment.
Storage Condition
Store between 20-25° C. Protect from light.
Innovators Monograph
You find simplified version here Nuquin HP
Nuquin HP contains Hydroquinone see full prescribing information from innovator Nuquin HP Monograph, Nuquin HP MSDS, Nuquin HP FDA label
FAQ
What is Nuquin HP used for?
Nuquin HP is used to lighten the dark patches of skin (also called hyperpigmentation, melasma, "liver spots," "age spots," freckles) caused by pregnancy, birth control pills, hormone medicine, or injury to the skin. Nuquin HP also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C₆H₄(OH)₂. It has two hydroxyl groups bonded to a benzene ring in a para position.
How safe is Nuquin HP?
Nuquin HP is deemed safe in the United States. There isn't any clinical evidence currently to suggest that Nuquin HP is harmful to humans. However, minor side effects are still possible. It may cause a temporary uptick in redness or dryness at first, especially if you have sensitive skin.
How does Nuquin HP work?
Nuquin HP bleaches your skin by decreasing the number of melanocytes present.
What are the common side effects of Nuquin HP?
Common side effects of Nuquin HP include:
- Mild skin irritation and sensitization (burning, stinging)
- Dermatitis.
- Dryness.
- Redness.
- Inflammatory reaction.
Is Nuquin HP safe during pregnancy?
Whitening and brightening solutions with Nuquin HP are safe to use during pregnancy and won't harm the foetus.
Is Nuquin HP safe during breastfeeding?
Nuquin HP is not contraindicated during breastfeeding and if Nuquin HP is required by the mother, it is not a reason to discontinue breastfeeding. However, some experts feel that long-term use of Nuquin HP is difficult to justify in a nursing mother.
Can Nuquin HP make me blind?
Inhaling Nuquin HP can irritate the nose and throat.
Is Nuquin HP hazardous?
Nuquin HP is also a skin irritant in humans. Chronic (long-term) occupational exposure to Nuquin HP dust can result in eye irritation, corneal effects, and impaired vision.
Can I leave Nuquin HP on overnight?
Apply Nuquin HP cream once daily to clean, dry skin, preferably at bedtime, and leave on overnight.
Can I use Nuquin HP everyday?
Nuquin HP a tyrosinase inhibitor, in a 4% cream can be used safely twice daily for up to 6 months to treat post-inflammatory hyperpigmentation. The efficacy of this treatment can be enhanced by using a retinoid nightly and a mid-potent steroid, which is applied twice daily for 2 weeks, then at weekends only.
How fast does Nuquin HP work?
It takes about four weeks on average for the ingredient to take effect.
How long should I use Nuquin HP?
You can use the product for up to four months, and then begin to taper off use.
Can Nuquin HP be used in the morning?
Apply Nuquin HP in the evening after Retin-A and in the morning for 2 to 6 weeks prior to the procedure.
How often can I use Nuquin HP?
Nuquin HP a tyrosinase inhibitor, in a 4% cream can be used safely twice daily for up to 6 months to treat post-inflammatory hyperpigmentation.
How long does Nuquin HP take to work?
Nuquin HP takes about four weeks on average for the ingredient to take effect.
Can I take Nuquin HP for long time?
You shouldn't use products with this ingredient for more than five months at a time.
When should I stop taking Nuquin HP?
Nuquin HP stop application after five months. If your skin lightens, stop using Nuquin HP regularly and only use it if the dark spots reappear. Wait two or three months to use it in the same areas.
Who should not take Nuquin HP?
Do not use Nuquin HP topical on open wounds or on sunburned, windburned, dry, chapped, or irritated skin. Call your doctor if your symptoms do not improve after 2 months, or if your condition gets worse.
What happens if I miss a dose?
Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.
What happens if I overdose of Nuquin HP?
An overdose of Nuquin HP topical is not expected to be dangerous. Seek emergency medical attention if anyone has accidentally swallowed the medication.
What happen If I stop taking Nuquin HP?
Prolonged regular use of Nuquin HP may lead to exogenous ochronosis, which can cause blue-black pigmentation and papules, red bumps on the skin.
Is Nuquin HP hard on my heart?
Nuquin HP can cause dangerous effects on your heart, especially if you also use certain other medicines. Seek emergency medical attention if you have fast or pounding heartbeats and sudden dizziness
Can Nuquin HP affect my kidneys?
Nuquin HP produce significant histological alterations that might affect the liver and kidney.
Can Nuquin HP affects my liver?
Nuquin HP can remove the top layer of skin, increasing the risk of skin cancer and cause fatal liver and kidney damage.
