Obiltoxaximab

Obiltoxaximab Uses, Dosage, Side Effects, Food Interaction and all others data.

Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin. Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis toxin. It has an approximate molecular weight of 148 kDa.

Obiltoxaximab
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
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Interaction With other Medicine
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Trade Name	Obiltoxaximab
Generic	Obiltoxaximab
Obiltoxaximab Other Names	Obiltoxaximab
Type	Intravenous
Weight	148000.0 Da
Groups	Approved
Therapeutic Class
Manufacturer
Available Country	United States
Last Updated:	September 19, 2023 at 7:00 am

Uses

Obiltoxaximab is a monoclonal antibody used for prophylaxis or treatment of inhalational anthrax.

Investigated for use/treatment in anthrax exposure, bacterial infection, crohn's disease, and graft versus host disease.

Obiltoxaximab is also used to associated treatment for these conditions: Inhaled anthrax caused by Bacillus anthracis

How Obiltoxaximab works

ETI-204 is an affinity-enhanced, de-immunized antibody, which means that its ability to bind to its target pathogen has been strengthened and that elements that might cause an immune response have been removed. ETI-204 targets and binds to Protective Antigen, which prevents the anthrax toxins from binding to and entering the cells in the body, thereby preventing death.