Obiltoxaximab

Obiltoxaximab Uses, Dosage, Side Effects, Food Interaction and all others data.

Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin. Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis toxin. It has an approximate molecular weight of 148 kDa.

Trade Name Obiltoxaximab
Generic Obiltoxaximab
Obiltoxaximab Other Names Obiltoxaximab
Type Intravenous
Weight 148000.0 Da
Groups Approved
Therapeutic Class
Manufacturer
Available Country United States
Last Updated: September 19, 2023 at 7:00 am
Obiltoxaximab
Obiltoxaximab

Uses

Obiltoxaximab is a monoclonal antibody used for prophylaxis or treatment of inhalational anthrax.

Investigated for use/treatment in anthrax exposure, bacterial infection, crohn's disease, and graft versus host disease.

Obiltoxaximab is also used to associated treatment for these conditions: Inhaled anthrax caused by Bacillus anthracis

How Obiltoxaximab works

ETI-204 is an affinity-enhanced, de-immunized antibody, which means that its ability to bind to its target pathogen has been strengthened and that elements that might cause an immune response have been removed. ETI-204 targets and binds to Protective Antigen, which prevents the anthrax toxins from binding to and entering the cells in the body, thereby preventing death.

Food Interaction

No interactions found.

Innovators Monograph

You find simplified version here Obiltoxaximab

*** Taking medicines without doctor's advice can cause long-term problems.
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