Octocrylene

Octocrylene Uses, Dosage, Side Effects, Food Interaction and all others data.

Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin damage from prolonged sun exposure. Octocrylene is also often combined with avobenzone, another common sunscreen ingredient often appearing on ingredient labels. Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and skin care products, but the concentrations of this ingredient are usually limited to no more than 10 or 12 percent. However, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend to a variety of other products, like hair spray, tannin oil, BB cream, conditioner, and CC cream, among others. Octocrylene may cause contact and photocontact allergy.

Trade Name Octocrylene
Generic Octocrylene
Octocrylene Other Names Octocrileno, Octocrilenum, Octocrylene
Type
Formula C24H27NO2
Weight Average: 361.485
Monoisotopic: 361.204179113
Protein binding

Ecamsule is only used topically, it not absorbed.

Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Octocrylene
Octocrylene

Uses

Octocrylene is a sunscreen agent found in sunscreens that absorbs UV rays.

In the US, Octocrylene has been evaluated by the FDA and is considered safe for use up to 10% in the formula. Similarly, the EU allows its use up to 10% in a formula while Health Canada allows a maximum use level of 12%.

Octocrylene is also used to associated treatment for these conditions: Sunburn

How Octocrylene works

Octocrylene is an effective oil soluble liquid UV‐B filter. It has excellent dissolving properties for crystalline UV filters. Due to its outstanding photostability it is used as photostabilizer. Conjugated acrylate portion absorbs UVB and short-wave UVA (ultraviolet) rays with wavelengths in the range of 280-320 nm which protects the skin from direct DNA damage. The ethylhexanol portion is a fatty alcohol, which functions as an emollient due to it's hydrophobicity.

Toxicity

Octocrylene is one of those ingredients that can be absorbed into the skin and some studies have shown that it may promote generation of potentially harmful free radicals when exposed to light. Since free radicals can damage DNA, there is concern that this ingredient might have contributed to an increased incidence of melanoma in sunscreen-users compared to non-users.

Food Interaction

No interactions found.

Volume of Distribution

Ecamsule is only used topically, it not absorbed.

Elimination Route

Ecamsule is used topically, it not absorbed or metabolized.

Half Life

Ecamsule is only used topically, it does not have half life

Clearance

Ecamsule is used topically, it not absorbed or metabolized.

Elimination Route

Ecamsule is used topically, it not absorbed.

Innovators Monograph

You find simplified version here Octocrylene

*** Taking medicines without doctor's advice can cause long-term problems.
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