Odevixibat
Odevixibat Uses, Dosage, Side Effects, Food Interaction and all others data.
Odevixibat is under investigation in clinical trial NCT04336722 (Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD)).
| Trade Name | Odevixibat |
| Availability | Prescription only |
| Generic | Odevixibat |
| Odevixibat Other Names | Odevixibat |
| Related Drugs | Bylvay |
| Type | |
| Formula | C37H48N4O8S2 |
| Weight | Average: 740.93 Monoisotopic: 740.29135687 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Food Interaction
[Moderate] MONITOR: Odevixibat may affect absorption of fat-soluble vitamins (FSV) including vitamin A, D, E, and K.
In clinical studies, new onset or worsening of existing FSV deficiency was reported in 5% of placebo-treated patients, and in 16% of odevixibat-treated 120 mcg However, none of the odevixibat-treated 40 mcg If FSV deficiency is diagnosed, supplement with FSV. Odevixibat should be discontinued if FSV deficiency persists or worsens despite adequate FSV supplementation.
MANAGEMENT: Clinical and laboratory monitoring of FSV levels is recommended at baseline and during treatment with odevixibat.
Odevixibat multivitamins interaction
[Moderate] Odevixibat may affect absorption of fat-soluble vitamins (FSV) including vitamin A, D, E, and K.
In clinical studies, new onset or worsening of existing FSV deficiency was reported in 5% of placebo-treated patients, and in 16% of odevixibat-treated 120 mcg However, none of the odevixibat-treated 40 mcg If FSV deficiency is diagnosed, supplement with FSV. Odevixibat should be discontinued if FSV deficiency persists or worsens despite adequate FSV supplementation.
Clinical and laboratory monitoring of FSV levels is recommended at baseline and during treatment with odevixibat.
Innovators Monograph
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