Oktafluorpropan Uses, Dosage, Side Effects and more

Oktafluorpropan, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Oktafluorpropan enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.

Oktafluorpropan, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. It provide contrast enhancement of the endocardial borders during echocardiography. The perflutren lipid microspheres exhibit lower acoustic impedance than blood and enhance the intrinsic backscatter of blood.

Trade Name	Oktafluorpropan
Availability	Prescription only
Generic	Perflutren
Perflutren Other Names	Freon 218, Octafluoropropane, Octafluorpropan, Oktafluorpropan, Perfluoropropane, Perflutren, Perflutreno
Related Drugs	Definity, Optison
Type
Formula	C₃F₈
Weight	Average: 188.0193 Monoisotopic: 187.98722564
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	January 7, 2025 at 1:49 am

Uses

Oktafluorpropan is a diagnostic medication to improve contrast during echocardiograms.

Used as an ultrasound contrast imaging in cardiology and radiology.

How Oktafluorpropan works

Oktafluorpropan is comprised of gas-filled microspheres that are injected or infused into the body. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Oktafluorpropan enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.

Toxicity

There is new temporal evidence that perflutren may be associated with new-onset seizure activity following perflutren microbubble contrast injection during dobutamine-atropine stress echocardiography. [PMID: 23432576]