One
One Uses, Dosage, Side Effects, Food Interaction and all others data.
One acts as an antioxidant by dual mode of action. It suppresses singlet oxygen and also inhibits lipid peroxidation. By these actions it reduces the harmful free radicals. Therefore acts as a very strong antioxidant. One is absorbed by passive diffusion into the intestinal epithelium alongside fatty acids. Then it is incorporated into lipoproteins, transported to the liver, via lymph and blood and partly resecreted with lipoproteins. More than 70% of the One is contained in high-density lipoprotein part of plasma. Highest concentration of One is in the small intestine, followed by subcutaneous fat, spleen, liver, heart, kidney and skin and lowest in the muscles.
Trade Name | One |
Generic | Astaxanthin |
Weight | 1.25mg |
Type | Tablet, Granules, Junior Syrup |
Formula | C40H52O4 |
Weight | Average: 596.852 Monoisotopic: 596.386560154 |
Groups | Investigational |
Therapeutic Class | Supplements & adjuvant therapy |
Manufacturer | Astra Idl Limited, Lahore Pharma |
Available Country | India, Pakistan |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
One is used to-
1. Strong antioxidant
2. Improves cardiovascular health (Atherosclerosis, reduce cholesterol).
3. Improves immune function.
4. Improves condition of skin
5. Protects skin from damage caused by sun (Reduce wrinkles, pimples and other signs of aging)
6. Improves recovery from central nervous system injuries
7. Protects from Parkinson ’s disease, Dementia and Alzheimer\'s
8. Protects eyes from cataracts and macular degeneration.
9. Reduces inflammation (Arthritis)
10. Reduces risk of infertility
Also Astaxnthin effectively reduce oxidative damage to DNA, decrease the risk for many types of cancer and stabilize blood sugar.
Dosage
One dosage
Adults (18 years and older) - Daily dose is 4mg. should be taken along with or immediately prior to meals in the morning.
Different dose for various use are given below:
4 mg: Used as a strong antioxidant, improves cardiovascular health (Atherosclerosis, reduce cholesterol), improves immune function.
4-8 mg: Improves condition of skin, protects skin from sun damage (Reduce wrinkles, pimples and other signs of aging), improves recovery from central nervous system injuries and protects eyes from cataracts and macular degeneration.
8-12 mg: Reduces inflammation (Arthritis)
16 mg: Reduces risk of infertility
Side Effects
No severe side effects have been reported yet
Precaution
Pregnant women and nursing mothers should avoid One containing supplements.
Interaction
Concomitant intake of One with Cholestyramine, Colestipol, Mineral oil, Orlistat may reduce the absorption rate of One
Food Interaction
No interactions found.Pregnancy & Breastfeeding use
Both pregnant women and lactating mothers should avoid One supplements as no data on safety has been found yet
Contraindication
Contraindicated for those with known allergies to One
Acute Overdose
No case of overdose has occurred with One
Interaction with other Medicine
Concomitant intake of One with Cholestyramine, Colestipol, Mineral oil, Orlistat may reduce the absorption rate of One
Storage Condition
Store in cool and dry place, away from direct light. Keep out of reach of children.
Innovators Monograph
You find simplified version here One
FAQ
What are the benefits of taking One?
An antioxidant, One is said to have many health benefits. It's been linked to healthier skin, endurance, heart health, joint pain, and may even have a future in cancer treatment.
Can I take One everyday?
One is possibly safe when taken by mouth as a supplement. One has been used safely by itself in doses of 4 to 40 mg daily for up to 12 weeks, or 12 mg daily for 6 months.
When should I take One?
One Dosage Adults (18 years and older) - Daily dose is 4mg. should be taken along with or immediately prior to meals in the morning.
Does One make me gain weight?
Natural astaxanthin has been shown to inhibit weight-gain and other markers linked with a high fat diet.
Is One worth taking?
One is one of the most sought-after antioxidant supplements right now – and with good reason. It's not only an antioxidant powerhouse but also jam-packed with anti-fatigue and anti-inflammatory properties, as well as an array of other health benefits.
How long does One take to work?
You'll have to use One at least two weeks and more likely four to as much as eight weeks to get the desired results. Fortunately, although Natural Astaxanthin takes longer to work than prescription anti- inflammatories and over-the-counter pain remedies, it is completely safe.
Is One safe for kidneys?
One(ATX) is a xanthophyll carotenoid of predominantly marine origin, with potent antioxidant and anti-apoptosis effects demonstrated in both experimental and human studies. Many studies have proven that astaxanthin has a preventive effect on various kidney diseases
Does One make me lose weight?
One at levels of 6 mg/kg or 30 mg/kg body weight significantly reduced the body weight gain induced by the high-fat diet. In addition, One reduced liver weight, liver triacyglycerol, plasma triacyglycerol and total cholesterol.
Is One good for my eyes?
One offers unique protection for the eye as one of the more efficient antioxidant compounds it neutralizes the oxygen radical molecules. One works with other vision health-supporting carotenoids, especially lutein and zeaxanthin.
Does One improve skin?
One scavenges the ROS in the skin surface which ultimately helps reduce moisture loss and keeps skin smooth. 2. Natural astaxanthin reduces UVB induced inflammation probably via the NF-kB kinase dependent pathway. The less stressed the skin is the better.
Does One lower testosterone?
Some laboratory studies have shown One may hinder an enzyme called 5-alpha-reductase. As a result, it could keep testosterone from changing into the hormone DHT in the body.
Is One good for immune system?
One has a strong ability to both balance and strengthen the immune system, therefore improving its ability to defend the body whilst also helping to suppress the overactive immune responses that create unwanted inflammation.
Will One turn me pink?
One is the compound that gives salmon and flamingos their pink hue. Proponents claim that in people, it has the power to reduce inflammation and oxidative damage to cells, which in turn preserves the eyes, skin, joints and central nervous system.
Is One an anti inflammatory?
One is a natural lipid-soluble and red-orange carotenoid. Due to its strong antioxidant property, anti-inflammatory, anti-apoptotic, and immune modulation, One has gained growing interest as a multi-target pharmacological agent against various diseases.
What is the best source of astaxanthin?
Shrimp, crab and salmon can serve as dietary sources of astaxanthin. Wild caught salmon is a good source of astaxanthin. In order to get 3.6 mg of astaxanthin one can eat 165 grams of salmon per day. Astaxanthin supplement at 3.6 mg per day can be beneficial to health as reported by Iwamoto et al.
Does One accumulate in the body?
Dietary One accumulated in the hippocampus and cerebral cortex of rat brains after single and repeated ingestion. One is more potent than other natural antioxidants such as alpha-tocopherol and beta-carotene.
Is One the strongest antioxidant?
Natural astaxanthin is the most powerful antioxidant known to science, and has the ability to optimize the health and radiance of the skin by providing protection and support to all layers.
Can I take One with fish oil?
No interactions were found between One and Fish Oil.
Does One interact with any medications?
No well-documented interactions have been identified apart from a potential to interact with hormone altering drugs such as a 5-alpha-reductase inhibitor. With extreme doses (48mg daily) feces may turn a reddish hue due to the red pigmentation of One.
What does One smell like?
Astaxanthin is a naturally occurring carotenoid well known for its therapeutic benefits and antioxidant properties. It is pretty, but it is also stinky. Astaxanthin smells fishy, so it has typically been found in tablets and softgels, which removes the ingredient from much of consumers' marketplace.
Does One raise cholesterol?
One has been reported to inhibit low-density lipoprotein (LDL) oxidation and to increase high-density lipoprotein (HDL)-cholesterol and adiponectin levels in clinical studies.
Is One good for nerve damage?
One improved learning and decreased memory impairment and neuronal damage.
Does One lighten skin?
One also helps lighten dark spots. It is a potent protection against ultraviolet radiation, assisting the skin in protecting itself against damage by the sun. Simply put, it lightens age spots by preventing too much melanin.
Can One reverse aging?
The anti-inflammatory activity of One, which is based on its antioxidant properties, has been implicated in improving lifestyle-related diseases and managing health. Furthermore, astaxanthin has anti-aging effects.
Is One good for testosterone?
One administration increased testosterone, GST and SOD levels and testis weight and decreased MDA concentration.
Can I take One with blood thinners?
Patients who take other drugs that may also affect bleeding including anticoagulants should use One with caution or make dosage adjustments. Therefore, potential adverse events of bleeding complications after One was administered along with warfarin may occur and should not be ignored.
Can I take One while on birth control?
One may inhibit Helicobacter pylori growth and have an additive effect when taken with other medications that have a similar effect. One may have hormonal effects and may interact with other hormone-altering medications, such as medications taken for menopause or birth control pills.
Does One help glaucoma?
Evidence that One can be effective in the treatment of Glaucoma. In one laboratory study rats with experimentally induced elevated IOP were given One in doses well beyond what would normally be consumed by humans.
Does One have Omega 3?
While fish oil is typically a shade of yellow, a naturally occurring antioxidant called astaxanthin gives krill oil a reddish color. Krill oil is a supplement that contains the omega-3 fatty acids EPA and DHA. The chemical structure of its fatty acids and red color set it apart from fish oil.
How to store One?
Freeze-drying led to 41% higher One recovery compared to commonly-used spray-drying. Low storage temperature (-20°C, 4°C) and vacuum-packing also showed higher One stability with as little as 12.3±3.1% degradation during 20weeks of storage.
Is One good for my brain?
Natural astaxanthin has been shown to improve brain and cognitive health. Randomized double-blind, placebo-controlled studies have shown that 3-months supplementation of natural astaxanthin (12 mg/daily) improved memory, mental quickness and multitasking in senior subjects complaining of age-related forgetfulness (2).