Opti Fusion
Opti Fusion Uses, Dosage, Side Effects, Food Interaction and all others data.
This eye drops has a unique combination of a natural lubricant, sodium hyaluronate and a most prominent ocular lubricant carboxymethylcellulose for instant relief & healthy tear film. It delivers sustained ocular protection and comfort with new Bridged Matrix technology to synergistically relieve the symptoms of dry eye. This eye drops provides properties of hydration, protection & restoration of eye surface integrity in any type of dry eye symptoms. It is also suitable for the contact lenses wearersThis eye drops have a unique formula that blends several ocular lubricants (Sodium Hyaluronate and Carboxymethylcellulose) to lubricate, protect and restore eye surface integrity. Sodium Hyaluronate is a natural polymer with viscoelastic property that promotes healing and guards against dehydration on the eye surface. Carboxymethylcellulose is one of the strongest mucoadhesive polymers, which retains direct contact with corneal epithelial cells to provide long-lasting clinical benefits.
| Trade Name | Opti Fusion |
| Generic | Sodium Hyaluronate + Carboxymethylcellulose |
| Weight | 0.1%+0.5% |
| Type | Ophthalmic Solution |
| Therapeutic Class | Drugs for Dry eyes |
| Manufacturer | Aristopharma Ltd, |
| Available Country | Bangladesh |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
This eye drops is useful for the instant relief of dry, irritated and gritty eyes which is compatible with contact lenses.
Pediatric use: Safety and effectiveness have not been demonstrated with this eye drops in pediatric patients.
Opti Fusion is also used to associated treatment for these conditions: Dry Eyes, Ocular Irritation
How Opti Fusion works
Carboxymethylcellulose binds to the surface of corneal epithelial cells via its glucopyranose subunits binding to glucose receptors GLUT-1 . The residence time of carboxymethylcellulose bound to corneal cells is approximately 2 hours as indicated by a short-term binding assay . Binding of carboxymethylcellulose to the matrix proteins stimulated corneal epithelial cell attachment, migration, and re-epithelialization of corneal wounds .
Dosage
Opti Fusion dosage
Instill 1 or 2 drops in the affected eye(s) as needed.
Side Effects
The chance of side effect is highly unlikely. However, transient blurring of vision may occur.
Toxicity
Rat oral LD50, rabbit dermal LD50, and rat inhalation LC50 of sodium carboxymethyl cellulose are 27000 mg/kg, >2 g/kg, and >5800 mg/m^3 (4 hours), respectively .
Precaution
- For ophthalmic use only.
- To avoid possible contamination of the drops, do not touch the dropper tip or to any surface. Replace the cap after use.
- Do not use if solution changes color or becomes cloudy.
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least five (5) minutes interval between applications.
Interaction
No information is available.
Volume of Distribution
No pharmacokinetic data available.
Elimination Route
No pharmacokinetic data available.
Half Life
No pharmacokinetic data available.
Clearance
No pharmacokinetic data available.
Elimination Route
No pharmacokinetic data available.
Pregnancy & Breastfeeding use
There are no adequate and well-controlled studies in pregnant women. This eye drops should be used during pregnancy unless the potential benefit justifies the potential risk to the fetus. It is not clear if enough medication from the eye drops would pass into breast milk. Caution should be exercised while giving this ophthalmic solution to a nursing mother.
Contraindication
This eye drops is contraindicated in patients who are hypersensitive to any component of Opti Fusion Sodium.
Special Warning
Use in children: No information available.
Use in elderly patients: No information available.
Acute Overdose
Since CMC is pharmacologically inert and not expected to be absorbed systemically, systemic effects from topical overdose are not expected from the administration of Carboxymethylcellulose sodium (Cellufresh) 0.5%. Additionally, no toxic side effects are expected should accidental systemic overdose occur.
No case of over dosage has been reported to date.
Storage Condition
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Innovators Monograph
You find simplified version here Opti Fusion
