Oral Varelon

Oral Varelon Uses, Dosage, Side Effects, Food Interaction and all others data.

Parenteral inactivated poliovirus vaccine(IPV) chiefly induces formation of serum antibody. Infection, with oral poliovirus vaccine (OPV) or wild poliovirus, also induces development of secretory IgA antibody. In addition, infection results in virus shedding and, hence, in possible spread of virus to contacts (more likelywith wild than with vaccine virus). IPV induces a high level (90%–95%) of protection against disease, which presumably is mediated by serum antibody that prevents CNS invasion resulting from viremia. IPV induces little protection against infection but does modify the related virus shedding- chiefly that from the oropharynx. Infection, whether by OPV or wild virus, induces a high level of protection against disease. It also results in appreciable prevention or modification of infection because of the developmentof secretoryIgA antibody. This effect is directly protective for the vaccinee and also benefits the community, since the exposed vaccinee can play little or no part in the spread of wild virus. One major question remaining concerns the maintenance of immunity. Lifelong immunologic memory assures an enhanced serum antibody response to any infection that occurs, but will it be sufficiently rapid that when preinfection antibody cannot be detected newly formed antibody will block blood-borne viral invasion of the CNS? If not, booster doses of vaccineare indicated. OPV boosters might be indicated in any case to reinforce protection against infection and so maintain herd immunity.

Oral Varelon
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Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
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Trade Name	Oral Varelon
Generic	Oral Polio Vaccine
Oral Polio Vaccine Other Names	OPV
Weight	1 dose=2drop=0.1 ml
Type	Drops
Groups	Investigational
Therapeutic Class	Vaccines, Anti-sera & Immunoglobulin
Manufacturer	CSL Behring, U,S,A,
Available Country	Bangladesh
Last Updated:	September 19, 2023 at 7:00 am

Uses

A suspension of suitable live attenuated strains of poliomyelitis virus, type 1,2 & 3; available as single dose and 5 doses ampoules.

Polio vaccines are vaccines used to prevent poliomyelitis (polio)

There are two types of vaccine that protect against polio: Inactivated Polio Vaccine (IPV) and Oral Varelon (OPV).

How Oral Varelon works

The polio vaccine allows for the encounter of the polio virus by the immune system to be less threatening while still allowing for the body to mount a humoral response for protection against any future exposure of the virus. For the OPV specifically, upon administration, the vaccine elicits a local immune response in the intestinal mucous membranes, a location at which the poliovirus multiplies. Antibodies produced locally then will inhibit multiplication of following infections of the wildtype poliovirus.