Orazinc 110(obsolete)
Orazinc 110(obsolete) Uses, Dosage, Side Effects, Food Interaction and all others data.
Orazinc 110(obsolete) is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Orazinc 110(obsolete) is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.
Although it has been nasally administered for treating the common cold, this route of administration has been associated with some cases of anosmia , , , .
Studies show that zinc may be better absorbed in humans in the gluconate form , , however, results from other studies may vary , [L27280].
Trade Name | Orazinc 110(obsolete) |
Generic | Zinc gluconate |
Zinc gluconate Other Names | Zinc gluconate |
Weight | 10mg, 23mg, 10mg, 100mg, 15mg, 22mg, 22.5mg, 25mg, 30mg, 50mg, 60mg, 78mg |
Type | Oral lozenge, oral tablet |
Formula | C12H22O14Zn |
Weight | Average: 455.67 Monoisotopic: 454.030097 |
Protein binding | Please refer to DrugBank entry Zinc |
Groups | Approved, Vet approved |
Therapeutic Class | |
Manufacturer | |
Available Country | United States |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Orazinc 110(obsolete) is an ingredient found in a variety of supplements and vitamins.
Orazinc 110(obsolete) is mainly indicated in conditions like zinc deficiency, and can also be administered in adjunctive therapy as an alternative drug of choice in diarrhea .
Orazinc 110(obsolete) is also used to associated treatment for these conditions: Zinc Deficiency
How Orazinc 110(obsolete) works
Although the mechanism of action is not completely known, zinc supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV) .
Toxicity
Nausea, vomiting, diarrhea, and mouth irritation have been reported in patients ingesting zinc gluconate tablets that were dissolved in the mouth for management the common cold .
Zinc crosses the placenta and is found the cord blood and placenta. Fetal concentrations are regulated by the placenta .
For more information, refer to Please refer to DrugBank entry Zinc.
Acute: 1290 mg/kg in mouse
Food Interaction
- Avoid milk and dairy products. Separate the use of zinc from these products by at least 2 hours before administration. Separate for 2 hours after administration if these products also contain phosphorus.
- Do not take with bran and high fiber foods. For optimal absorption, take zinc at least 2 hours before or after eating high-fiber foods.
- Take on an empty stomach. Take at least 1 hour before and 2 hours after eating for optimal absorption. Zinc can be taken with food to reduce gastrointestinal upset.
Volume of Distribution
Stored primarily in skeletal muscle and bone .
Elimination Route
Please refer to DrugBank entry Zinc
Half Life
280 days
Clearance
Please refer to DrugBank entry Zinc
Elimination Route
Feces and urine
Innovators Monograph
You find simplified version here Orazinc 110(obsolete)