Oroxat Tablet 20 mg

Oroxat Tablet 20 mg Uses, Dosage, Side Effects, Food Interaction and all others data.

FibroGen completed the phase I single-dose, dose escalation studies as of July 2007. Multiple dose, dose escalation and phase II US studies are listed as ongoing.

FG-4592 represents one of several next generation PHI that has been optimized for multiple pharmacokinetic and pharmacodynamic parameters related to erythropoiesis, including selective inhibition of HIF prolyl and asparaginyl hydroxylases, potency, iron utilization, and ADME. FG-4592 represents one of several next generation HIF-PH inhibitors designed to selectively induce the expression of genes that mediate erythropoiesis for the treatment of anemia.

Trade Name Oroxat Tablet 20 mg
Generic Roxadustat
Roxadustat Other Names Roxadustat, Roxadustatum
Weight 20 mg
Type Tablet
Formula C19H16N2O5
Weight Average: 352.346
Monoisotopic: 352.105921623
Groups Investigational
Therapeutic Class
Manufacturer Eskayef Pharmaceuticals Ltd.
Available Country Bangladesh
Last Updated: October 19, 2023 at 6:27 am
Oroxat Tablet 20 mg
Oroxat Tablet 20 mg

Uses

In clinical development for the treatment of anemia of chronic inflammatory disease.

How Oroxat Tablet 20 mg works

FG-4592 is an orally active second generation HIF-PH inhibitor. Preclinical studies show that FG-4592 increases production of endogenous erythropoietin (EPO), increases iron mobilization and utilization, and overcomes the suppressive effects of inflammation on red blood cell production.

Elimination Route

Orally active

Innovators Monograph

You find simplified version here Oroxat Tablet 20 mg

*** Taking medicines without doctor's advice can cause long-term problems.
Share