Orthorate

Orthorate Uses, Dosage, Side Effects, Food Interaction and all others data.

Orthorate contains Calcium Orotate, a calcium supplement with a functional amino acid chelating ligand - orotic acid. Orotic acid assists the transport of calcium through cellular membrane structures, facilitating the intracellular uptake of calcium, particularly in bone. Calcium Orotate also helps in the maintenance of healthy cartilage. Furthermore, Orotate is involved in the synthesis of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). Calcium Orotate has the ability to penetrate complex cell membranes and it can be metabolized in cartilage.

Orthorate
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Orthorate
Generic	Calcium Orotate Dihydrate
Weight	400mg
Type	Tablet
Therapeutic Class	Minerals in bone formation, Specific mineral preparations
Manufacturer	Biopharma Laboratories Ltd
Available Country	Bangladesh
Last Updated:	September 19, 2023 at 7:00 am

Uses

Orthorate is used -

1. To prevent or treat low blood calcium levels in people who do not

get enough calcium from diets.

2. To fulfill the calcium deficiency or meet extra need of calcium in

conditions like-

• Osteomalacia

• Rickets

• Latent tetany

• Postmenopausal osteoporosis

• Senile osteoporosis

• Juvenile osteoporosis

• Drug induced osteoporosis

(Phenytoin, Phenobarbital, or Prednisone)

• Pregnancy and lactation

• Premenstrual syndrome (PMS)

• Hypoparathyroidism

• Hip joint plastic surgery

3. Acts against a number of inflammatory diseases like -

• Arthritis

• Multiple sclerosis

• Spondylitis

4. Helps in controlling weight by suppressing the habit of frequent

appetite of chronic overeaters.

5. It is also beneficial in reducing the effects of mood swings.

6. Proved to be quite effective in cognitive enhancement.

7. Protects the heart by enhancing the efficiency of cardiac muscles.

Dosage

Orthorate dosage

Calcium Orotate 400 mg: As an addition to the daily diet, 2-3 tablets are usually recommended with meal, after meal or as directed by physician.

Calcium Orotate 740 mg: As an addition to the daily diet, 1-2 tablets are usually recommended with meal, after meal or as directed by physician.

Side Effects

Bloating and swelling in the abdomen are common side effects of Calcium Orotate. Constipation, nausea, vomiting, headache, increased thirst/ urination, may occur infrequently.

Precaution

Before taking calcium, precaution is needed if the patient has any allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Precaution is needed before using this product in kidney disease, kidney stones, little or no stomach acid (achlorhydria), heart disease, disease of the pancreas, a certain lung disease(sarcoidosis), difficulty absorbing nutrition from food (malabsorption syndrome).

Interaction

Calcium can decrease absorption of the following drugs when taken together with bisphosphonates, quinolone antibiotics, tetracycline antibiotics, levothyroxine, phenytoin and tiludronate disodium. Thiazide-type diuretics can interact with Calcium supplements, increasing the risks of hypercalcemia and hypercalciuria.

Pregnancy & Breastfeeding use

During pregnancy and lactation treatment with Calcium Orotate should always be under the direction of a physician. Women who are pregnant and breast feeding need more Calcium. Pregnancy related high blood pressure is a common and serious risk for women and their babies. Taking supplement of Calcium Orotate can help to reduce this risk.

Contraindication

Calcium Orotate is contraindicated in conditions like kidney stone, kidney disease, increased activity of the parathyroid gland, high amount of Calcium in urine & blood and extreme loss of body water.

Acute Overdose

Symptoms of over dose may include nausea/ vomiting, weight loss, loss of appetite, constipation, headache, weakness etc if any of the side effects become serious please talk with physician.