Osvit L

Osvit L Uses, Dosage, Side Effects, Food Interaction and all others data.

A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

This compound is needed for good nerve conduction throughout the CNS (central nervous system) as it is a precursor to acetylcholine (ACh). Choline is also needed for gallbladder regulation, liver function and lecithin (a key lipid) formation. Choline also aids in fat and cholesterol metabolism and prevents excessive fat build up in the liver. Choline has been used to mitigate the effects of Parkinsonism and tardive dyskinesia. Choline deficiencies may result in excessive build-up of fat in the liver, high blood pressure, gastric ulcers, kidney and liver dysfunction and stunted growth.

Vitamin-B complex contains the most important members of the vitamin B group in pure form and in therapeutically balanced proportions. The members of the vitamin B group contained in Vitamin-B complex are components of enzyme systems that regulate various stages of carbohydrate, fat and protein metabolism, each of the components playing a specific biological role. Deficiency of B vitamin causes glossitis, stomatitis, cheilosis, polyneuritis, beriberi, pellagra and vascularisation of cornea.

Osvit L
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Osvit L
Generic	Choline + L-lysine + Vitamin B Complex
Type	Syrup
Therapeutic Class
Manufacturer	Oxford Pharmaceuticals Pvt Ltd
Available Country	India
Last Updated:	September 19, 2023 at 7:00 am

Uses

Choline is a nutrient found in a wide variety of vitamins including pre-natal formulations.

For nutritional supplementation, also for treating dietary shortage or imbalance

Each Tablet/ Capsule contains:

Thiamine Hydrochloride 5 mg
Riboflavin 2 mg
Pyridoxine hydrochloride 2 mg
Nicotinamide 20 mg

Each 5 ml Syrup contains:

Thiamine Hydrochloride 5 mg
Riboflavin 2 mg
Pyridoxine hydrochloride 2 mg
Nicotinamide 20 mg

Each 2 ml Injection contains:

Thiamine Hydrochloride 50 mg
Riboflavin 4 mg
Pyridoxine hydrochloride 10 mg
Nicotinamide 100 mg
D-Panthenol 5 mg

Vitamin-B complex is used for prophylactic or therapeutic nutritional supplementation in physiologically stressful conditions. These include: Conditions causing depletion, or reduced absorption or bioavailability of essential B-vitamins manifested by glossitis, stomatitis, cheilosis, beriberi Vitamin-B complex is used for prophylactic or therapeutic nutritional supplementation in physiologically stressful conditions. These include: Conditions causing depletion, or reduced absorption or bioavailability of essential B-vitamins manifested by glossitis, stomatitis, cheilosis, beriberi

Osvit L is also used to associated treatment for these conditions: Nutritional supplementation

How Osvit L works

Choline is a major part of the polar head group of phosphatidylcholine. Phosphatidylcholine's role in the maintenance of cell membrane integrity is vital to all of the basic biological processes: information flow, intracellular communication and bioenergetics. Inadequate choline intake would negatively affect all these processes. Choline is also a major part of another membrane phospholipid, sphingomyelin, also important for the maintenance of cell structure and function. It is noteworthy and not surprising that choline deficiency in cell culture causes apoptosis or programmed cell death. This appears to be due to abnormalities in cell membrane phosphatidylcholine content and an increase in ceramide, a precursor, as well as a metabolite, of sphingomyelin. Ceramide accumulation, which is caused by choline deficiency, appears to activate Caspase, a type of enzyme that mediates apoptosis. Betaine or trimethylglycine is derived from choline via an oxidation reaction. Betaine is one of the factors that maintains low levels of homocysteine by resynthesizing L-methionine from homocysteine. Elevated homocysteine levels are a significant risk factor for atherosclerosis, as well as other cardiovascular and neurological disorders. Acetylcholine is one of the major neurotransmitters and requires choline for its synthesis. Adequate acetylcholine levels in the brain are believed to be protective against certain types of dementia, including Alzheimer's disease.

Dosage

Osvit L dosage

Tablet/ capsule:usual recommended dose is 1-2 tablet/capsule 3 times daily or as directed by the physician.

Syrup:2-3 teaspoonful daily or as directed by the physician.

Injection:It is for intramuscular and intravenous administration. Usual recommended dose is 2 ml daily or as directed by the physician. In addition withThiamine, Riboflavin, Nicotinamide, Pyridoxine; injectable dosage from containsD-Panthenol 5 mg.

Side Effects

Adverse reactions have been reported with specific vitamins and minerals, but generally at levels substantially higher than those in Vitamin-B complex. However, allergic and idiosyncratic reactions are possible at lower levels. Iron, even at the usual recommended level has been associated with gastrointestinal intolerance in some patients.

Toxicity

Oral rat LD₅₀: 3400 mg/kg

Interaction

As little as 5 mg pyridoxine daily can decrease the efficacy of levodopa in the treatment of parkinsonism. Therefore, Vitamin-B complex is not recommended for patients undergoing such therapy