Otrivin Noscapine HCl

Otrivin Noscapine HCl Uses, Dosage, Side Effects, Food Interaction and all others data.

Table Of contents

• Otrivin Noscapine HCl
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Otrivin Noscapine HCl
Generic	Noscapine
Noscapine Other Names	alpha-Narcotine, Noscapina, Noscapine, Noscapinum
Type
Formula	C22H23NO7
Weight	Average: 413.4205 Monoisotopic: 413.147452095
Groups	Approved, Investigational
Therapeutic Class
Manufacturer	Novartis
Available Country	Netherlands
Last Updated:	September 19, 2023 at 7:00 am

Uses

Otrivin Noscapine HCl is a non-sedating isoquinoline alkaloid used primarily for its antitussive properties.

Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma.

Otrivin Noscapine HCl is also used to associated treatment for these conditions: Common Cold, Cough, Respiratory Diseases, Airway secretion clearance therapy

How Otrivin Noscapine HCl works

Otrivin Noscapine HCl's antitussive effects appear to be primarily mediated by its sigma receptor agonist activity. Evidence for this mechanism is suggested by experimental evidence in rats. Pretreatment with rimcazole, a sigma specific antagonist, causes a dose-dependent reduction in antitussive activity of noscapine.

Innovators Monograph

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