Oxasulfa

Oxasulfa Uses, Dosage, Side Effects, Food Interaction and all others data.

Oxasulfa is an antibacterial in the sulfonamide class.

Oxasulfa is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Oxasulfa
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Oxasulfa
Generic	Sulfamoxole
Sulfamoxole Other Names	2-(p-Aminobenzolsulfonamido)-4,5-dimethyloxazol, Oxasulfa, Sulfadimethyloxazole, Sulfamoxol, Sulfamoxole, Sulfamoxolum, Sulphamoxole
Type
Formula	C₁₁H₁₃N₃O₃S
Weight	Average: 267.304 Monoisotopic: 267.067761987
Groups	Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

For the treatment of bacterial infection.

How Oxasulfa works

Oxasulfa is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. This enzyme is needed for the proper processing of para-aminobenzoic acid (PABA) which is essential for folic acid synthesis. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.