Oxybuprocaine Hydrochloride 0.4% Nitto

Oxybuprocaine Hydrochloride 0.4% Nitto Uses, Dosage, Side Effects, Food Interaction and all others data.

Oxybuprocaine Hydrochloride 0.4% Nitto is a local anaesthetic. It may be less irritating than tetracaine, and the onset and duration of action are similar to tetracaine. Oxybuprocaine Hydrochloride 0.4% Nitto binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses.

Oxybuprocaine Hydrochloride 0.4% Nitto is a local anaesthetic. It may be less irritating than tetracaine, and the onset and duration of action are similar to tetracaine.

Trade Name Oxybuprocaine Hydrochloride 0.4% Nitto
Generic Oxybuprocaine
Oxybuprocaine Other Names Benoxinate, Oxibuprocaina, Oxybucaine, Oxybuprocaine, Oxybuprocainum, Oxyriprocaine
Type
Formula C17H28N2O3
Weight Average: 308.4158
Monoisotopic: 308.209992772
Groups Approved, Investigational
Therapeutic Class Ocular perioperative drugs
Manufacturer
Available Country Japan
Last Updated: September 19, 2023 at 7:00 am
Oxybuprocaine Hydrochloride 0.4% Nitto
Oxybuprocaine Hydrochloride 0.4% Nitto

Uses

Used to temporarily numb the front surface of the eye so that the eye pressure can be measured or a foreign body removed.

Oxybuprocaine Hydrochloride 0.4% Nitto is also used to associated treatment for these conditions: Local Anesthesia of the Mouth

How Oxybuprocaine Hydrochloride 0.4% Nitto works

Oxybuprocaine Hydrochloride 0.4% Nitto binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses.

Dosage

Oxybuprocaine Hydrochloride 0.4% Nitto dosage

Use as a 0.4% solution in short ophthalmic procedures. Instil 1 drop into the conjunctival sac to allow tonometry after 60 sec; a further drop after a 90 sec interval produces sufficiReduce systemic absorption by compressing the lacrimal sac at the medial canthus for a minute during and following instillation. Heart block; epilepsy, impaired cardiac conduction, myasthenia gravis; not to be applied to inflamed, infected tissues or damaged mucosa. Protect anaesthetised eye from dust and bacterial contamination; cornea may be damaged by prolonged application. Do not drive until normal vision restored.ent anaesthesia for the fitting of contact lenses; 3 drops at 90 sec intervals produces sufficient anaesthesia after 5 min for a foreign body to be removed from the corneal epithelium or for incision of a meibomian cyst through the conjunctiva.

Side Effects

Hypersensitivity reactions; transient stinging and blurring of vision; excitation of CNS; muscle twitching and tremors; convulsions.

Precaution

Reduce systemic absorption by compressing the lacrimal sac at the medial canthus for a minute during and following instillation. Heart block; epilepsy, impaired cardiac conduction, myasthenia gravis; not to be applied to inflamed, infected tissues or damaged mucosa. Protect anaesthetised eye from dust and bacterial contamination; cornea may be damaged by prolonged application. Do not drive until normal vision restored.

Food Interaction

No interactions found.

Pregnancy & Breastfeeding use

Pregnancy Category C. Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

*** Taking medicines without doctor's advice can cause long-term problems.
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