Palifosfamide

Palifosfamide Uses, Dosage, Side Effects, Food Interaction and all others data.

Palifosfamide (ZIO-201) is a proprietary stabilized metabolite of ifosfamide. Ifosfamide has been shown to be effective in high doses in treating testicular cancer, sarcoma and lymphoma.

Trade Name Palifosfamide
Generic Palifosfamide
Palifosfamide Other Names Ifosfamide mustard, Ifosforamide mustard, Isophosphamide mustard, Isophosphoramide mustard, Palifosfamide
Type
Formula C4H11Cl2N2O2P
Weight Average: 221.022
Monoisotopic: 219.993519532
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Palifosfamide
Palifosfamide

Uses

Investigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma.

How Palifosfamide works

After metabolic activation, palifosfamide alkylates or binds with many intracellular molecular structures, including nucleic acids. The cytotoxic action is primarily due to cross-linking of strands of DNA and RNA, as well as inhibition of protein synthesis.

Innovators Monograph

You find simplified version here Palifosfamide

*** Taking medicines without doctor's advice can cause long-term problems.
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