Pamine Forte
Pamine Forte Uses, Dosage, Side Effects, Food Interaction and all others data.
Pamine Forte is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Pamine Forte bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Pamine Forte bromide is an anticholinergic agent which possesses most of the pharmacologic actions of that drug class. These include reduction in volume and total acid content of gastric secretion, inhibition of gastrointestinal motility, inhibition of salivary excretion, dilation of the pupil and inhibition of accommodation with resulting blurring of vision. Large doses may result in tachycardia [Dailymed].
| Trade Name | Pamine Forte |
| Availability | Prescription only |
| Generic | Methscopolamine |
| Methscopolamine Other Names | Methylscopolamine |
| Related Drugs | famotidine, pantoprazole, Pepcid, Protonix, glycopyrrolate, Librax |
| Weight | 2.5mg, 5mg, |
| Type | Oral tablet |
| Formula | C18H24NO4 |
| Weight | Average: 318.392 Monoisotopic: 318.169984677 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | United States |
| Last Updated: | September 19, 2023 at 7:00 am |
Pamine Forte Alcohol interaction
[Moderate] GENERALLY AVOID:
Use of anticholinergic agents with alcohol may result in sufficient impairment of attention so as to render driving and operating machinery more hazardous.
In addition, the potential for abuse may be increased with the combination.
The mechanism of interaction is not established but may involve additive depressant effects on the central nervous system.
No effect of oral propantheline or atropine on blood alcohol levels was observed in healthy volunteers when administered before ingestion of a standard ethanol load.
However, one study found impairment of attention in subjects given atropine 0.5 mg or glycopyrrolate 1 mg in combination with alcohol.
Alcohol should generally be avoided during therapy with anticholinergic agents.
Patients should be counseled to avoid activities requiring mental alertness until they know how these agents affect them.
Pamine Forte Hypertension interaction
[Minor] Cardiovascular effects of anticholinergics may exacerbate hypertension.
Therapy with anticholinergic agents should be administered cautiously in patients with hypertension.
Pamine Forte Drug Interaction
Unknown: zolpidem, zolpidem, duloxetine, duloxetine, dexlansoprazole, dexlansoprazole, pregabalin, pregabalin, esomeprazole, esomeprazole, levothyroxine, levothyroxine, cyanocobalamin, cyanocobalamin, cholecalciferol, cholecalciferol, alprazolam, alprazolam, cetirizine, cetirizine
Pamine Forte Disease Interaction
Major: autonomic neuropathy, GI obstruction, glaucoma, obstructive uropathy, reactive airway diseases, myasthenia gravis, infectious diarrheaModerate: cardiac disease, tachycardia, coronary artery disease, gastric ulcer, gastroesophageal reflux, ulcerative colitisMinor: hypertension, hyperthyroidism, diarrhea, fever
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