Папаверина гидрохлорида таблетки для детей 0,01 г

Папаверина гидрохлорида таблетки для детей 0,01 г Uses, Dosage, Side Effects, Food Interaction and all others data.

An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.

Папаверина гидрохлорида таблетки для детей 0,01 г is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Папаверина гидрохлорида таблетки для детей 0,01 г are exerted on cardiac and smooth muscle. Like qathidine, Папаверина гидрохлорида таблетки для детей 0,01 г acts directly on the heart muscle to depress conduction and prolong the refractory period. Папаверина гидрохлорида таблетки для детей 0,01 г relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Папаверина гидрохлорида таблетки для детей 0,01 г and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Папаверина гидрохлорида таблетки для детей 0,01 г is practically devoid of effects on the central nervous system. Папаверина гидрохлорида таблетки для детей 0,01 г relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.

Trade Name Папаверина гидрохлорида таблетки для детей 0,01 г
Availability Prescription only
Generic Papaverine
Papaverine Other Names Papaverina, Papaverine
Type
Formula C20H21NO4
Weight Average: 339.385
Monoisotopic: 339.147058165
Protein binding

~90%

Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country Russia
Last Updated: September 19, 2023 at 7:00 am
Папаверина гидрохлорида таблетки для детей 0,01 г
Папаверина гидрохлорида таблетки для детей 0,01 г

Uses

Папаверина гидрохлорида таблетки для детей 0,01 г is an alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".

For the treatment of impotence and vasospasms.

Папаверина гидрохлорида таблетки для детей 0,01 г is also used to associated treatment for these conditions: Vascular spasm, Visceral spasms

How Папаверина гидрохлорида таблетки для детей 0,01 г works

Perhaps by its direct vasodilating action on cerebral blood vessels, Папаверина гидрохлорида таблетки для детей 0,01 г increases cerebral blood flow and decreases cerebral vascular resistance in normal subjects; oxygen consumption is unaltered. These effects may explain the benefit reported from the drug in cerebral vascular encephalopathy.

Food Interaction

No interactions found.

Папаверина гидрохлорида таблетки для детей 0,01 г Disease Interaction

Major: complete AV heart blockModerate: glaucoma

Half Life

0.5-2 hours

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0000002
http://classyfire.wishartlab.com/tax_nodes/C0002566
http://classyfire.wishartlab.com/tax_nodes/C0000054
http://classyfire.wishartlab.com/tax_nodes/C0000054
http://classyfire.wishartlab.com/tax_nodes/C0004111
http://classyfire.wishartlab.com/tax_nodes/C0004742
http://classyfire.wishartlab.com/tax_nodes/C0000138
http://classyfire.wishartlab.com/tax_nodes/C0000128
http://classyfire.wishartlab.com/tax_nodes/C0000089
http://classyfire.wishartlab.com/tax_nodes/C0004144
http://classyfire.wishartlab.com/tax_nodes/C0004139
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0000278
http://classyfire.wishartlab.com/tax_nodes/C0004150
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:28241
http://www.genome.jp/dbget-bin/www_bget?cpd:C06533
http://www.hmdb.ca/metabolites/HMDB0015245
http://www.genome.jp/dbget-bin/www_bget?drug:D07425
http://www.genome.jp/dbget-bin/www_bget?cpd:C06533
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=4680
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508003
https://www.chemspider.com/Chemical-Structure.4518.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=14754
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=7895
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=28241
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL19224
https://zinc.docking.org/substances/ZINC000000056555
http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000959
http://www.pharmgkb.org/drug/PA164745550
https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/EV1
http://www.rxlist.com/cgi/generic/papaverine.htm
https://www.drugs.com/cdi/papaverine.html
https://en.wikipedia.org/wiki/Papaverine
*** Taking medicines without doctor's advice can cause long-term problems.
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