Папаверина гидрохлорида таблетки для детей 0,01 г
Папаверина гидрохлорида таблетки для детей 0,01 г Uses, Dosage, Side Effects, Food Interaction and all others data.
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Папаверина гидрохлорида таблетки для детей 0,01 г is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Папаверина гидрохлорида таблетки для детей 0,01 г are exerted on cardiac and smooth muscle. Like qathidine, Папаверина гидрохлорида таблетки для детей 0,01 г acts directly on the heart muscle to depress conduction and prolong the refractory period. Папаверина гидрохлорида таблетки для детей 0,01 г relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Папаверина гидрохлорида таблетки для детей 0,01 г and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Папаверина гидрохлорида таблетки для детей 0,01 г is practically devoid of effects on the central nervous system. Папаверина гидрохлорида таблетки для детей 0,01 г relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.
Trade Name | Папаверина гидрохлорида таблетки для детей 0,01 г |
Availability | Prescription only |
Generic | Papaverine |
Papaverine Other Names | Papaverina, Papaverine |
Type | |
Formula | C20H21NO4 |
Weight | Average: 339.385 Monoisotopic: 339.147058165 |
Protein binding | ~90% |
Groups | Approved, Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | Russia |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Папаверина гидрохлорида таблетки для детей 0,01 г is an alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
For the treatment of impotence and vasospasms.
Папаверина гидрохлорида таблетки для детей 0,01 г is also used to associated treatment for these conditions: Vascular spasm, Visceral spasms
How Папаверина гидрохлорида таблетки для детей 0,01 г works
Perhaps by its direct vasodilating action on cerebral blood vessels, Папаверина гидрохлорида таблетки для детей 0,01 г increases cerebral blood flow and decreases cerebral vascular resistance in normal subjects; oxygen consumption is unaltered. These effects may explain the benefit reported from the drug in cerebral vascular encephalopathy.
Food Interaction
No interactions found.Папаверина гидрохлорида таблетки для детей 0,01 г Drug Interaction
Major: ciprofloxacinModerate: arginine, sildenafilMinor: tadalafilUnknown: aspirin, epinephrine, contained in alcoholic beverages , aspirin, ubiquinone, rosuvastatin, fluticasone nasal, metoprolol, gabapentin, acetaminophen, thiamine, cyanocobalamin, pyridoxine, ascorbic acid, cholecalciferol, phytonadione
Папаверина гидрохлорида таблетки для детей 0,01 г Disease Interaction
Half Life
0.5-2 hours
Innovators Monograph
You find simplified version here Папаверина гидрохлорида таблетки для детей 0,01 г