Papaverine Hydrochloride Biosintez
Papaverine Hydrochloride Biosintez Uses, Dosage, Side Effects, Food Interaction and all others data.
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Papaverine Hydrochloride Biosintez is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Papaverine Hydrochloride Biosintez are exerted on cardiac and smooth muscle. Like qathidine, Papaverine Hydrochloride Biosintez acts directly on the heart muscle to depress conduction and prolong the refractory period. Papaverine Hydrochloride Biosintez relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Papaverine Hydrochloride Biosintez and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Papaverine Hydrochloride Biosintez is practically devoid of effects on the central nervous system. Papaverine Hydrochloride Biosintez relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.
| Trade Name | Papaverine Hydrochloride Biosintez |
| Availability | Prescription only |
| Generic | Papaverine |
| Papaverine Other Names | Papaverina, Papaverine |
| Type | |
| Formula | C20H21NO4 |
| Weight | Average: 339.385 Monoisotopic: 339.147058165 |
| Protein binding | ~90% |
| Groups | Approved, Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | Georgia |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Papaverine Hydrochloride Biosintez is an alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
For the treatment of impotence and vasospasms.
Papaverine Hydrochloride Biosintez is also used to associated treatment for these conditions: Vascular spasm, Visceral spasms
How Papaverine Hydrochloride Biosintez works
Perhaps by its direct vasodilating action on cerebral blood vessels, Papaverine Hydrochloride Biosintez increases cerebral blood flow and decreases cerebral vascular resistance in normal subjects; oxygen consumption is unaltered. These effects may explain the benefit reported from the drug in cerebral vascular encephalopathy.
Food Interaction
No interactions found.Papaverine Hydrochloride Biosintez Drug Interaction
Major: ciprofloxacinModerate: arginine, sildenafilMinor: tadalafilUnknown: aspirin, epinephrine, contained in alcoholic beverages , aspirin, ubiquinone, rosuvastatin, fluticasone nasal, metoprolol, gabapentin, acetaminophen, thiamine, cyanocobalamin, pyridoxine, ascorbic acid, cholecalciferol, phytonadione
Papaverine Hydrochloride Biosintez Disease Interaction
Half Life
0.5-2 hours
Innovators Monograph
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