Pegdinetanib

Pegdinetanib Uses, Dosage, Side Effects, Food Interaction and all others data.

CT-322 is a proprietary Adnectin(TM) protein therapeutic that, in preclinical studies, specifically binds to vascular endothelial growth factor receptor 2 (VEGFR-2), which regulates the primary tumor angiogenesis pathway. As a result, CT-322 blocks all known ligands for VEGFR-2.

Trade Name Pegdinetanib
Generic Pegdinetanib
Pegdinetanib Other Names Pegdinetanib
Type
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Pegdinetanib
Pegdinetanib

Uses

Investigated for use/treatment in cancer/tumors (unspecified) and macular degeneration.

How Pegdinetanib works

CT-322 specifically inhibits VEGFR-2 activation by its ligands VEGF-A, VEGF-C, and VEGF-D. In preclinical studies, this cell-surface receptor drives angiogenesis (growth of new blood vessels) in solid tumors, and CT-322 inhibits the tumorgenic effect of VEGFR-2 in preclinical models. CT-322 was designed using the PROfusion(TM) System, Adnexus' patented product design engine.

Innovators Monograph

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