PEP DT

PEP DT Uses, Dosage, Side Effects, Food Interaction and all others data.

Zinc oxide is used to treat or prevent minor skin irritations such as burns, cuts, poison ivy, poison oak, poison sumac, and diaper rash. It is also used as a sunscreen.

Zinc oxide has astringent, soothing and protective properties and is used in topical preparations for eczema, slight excoriations, wounds and haemorrhoids. It also reflects ultraviolet radiation and can be used as a physical sunscreen.

Trade Name PEP DT
Generic Zinc Oxide
Zinc Oxide Other Names óxido de cinc, oxyde de zinc, Zinc (as oxide), Zinc (as zinc oxide), Zinc oxide, Zinc óxido, Zinc white, Zinci oxydum, Zincum oxydatum, Zinkoxid
Type
Formula OZn
Weight Average: 81.408
Monoisotopic: 79.9240612
Protein binding

Intended for local use only, no systemic absorption.

Groups Approved
Therapeutic Class Drugs used in diaper rash, Emollients & combined preparations
Manufacturer
Available Country Bangladesh
Last Updated: September 19, 2023 at 7:00 am
PEP DT
PEP DT

Uses

PEP DT helps to To treat or prevent skin irritations (e.g., burns, bed sore, cuts, poison ivy, diaper rash). Protects chafed skin due to diaper rash and helps seal out wetness.

PEP DT is also used to associated treatment for these conditions: Acute Wounds, Burns first degree, Burns second degree, Dermatitis, Eczematous, Diaper Rash, Herpes Labialis, Injuries to the Nipple (Fissures and Cracks) Resulting Breastfeeding, Intertrigo, Pain, Pruritus, Sensitive Skin, Skin Irritation, Skin candida, Sunburn, Wounds, Chafing, Damaged skin, Dry, cracked skin, Facial rash, Heat rash, Superficial Wounds, Watery skin lesions, Astringent, Nutritional supplementation

How PEP DT works

It acts by providing a physical barrier to prevent skin irritation and help heal damaged skin.

Dosage

PEP DT dosage

Apply thin layer topically every 8 hourly. Change wet and soiled diapers, promptly cleans the diaper area, allow to dry and apply ointment liberally as often as necessary, with each diaper change, especially at bedtime or any time when exposure to wet diapers may be prolonged.

Side Effects

Usually well tolerated. Extremely low frequency of hypersensitivity reaction.

Toxicity

Acute oral toxicity (LD50): 7950 mg/kg [Mouse].

Precaution

For external use only. Avoid contact with the eyes. Stop use and ask a doctor if condition worsens or does not improve within 7 days. Keep out of the reach of children. If swallowed, get medical help or contact a poison control center right away

Food Interaction

  • Avoid milk and dairy products. Separate the use of zinc from these products by at least 2 hours before administration. Separate for 2 hours after administration if these products also contain phosphorus.
  • Do not take with bran and high fiber foods. For optimal absorption, take zinc at least 2 hours before or after eating high-fiber foods.
  • Take on an empty stomach. Take at least 1 hour before and 2 hours after eating for optimal absorption. Zinc can be taken with food to reduce gastrointestinal upset.

Volume of Distribution

Intended for local use only, no systemic absorption.

Elimination Route

No significant percutaneous absorption from topically applied zinc oxide.

Half Life

Intended for local use only, no systemic absorption.

Clearance

Intended for local use only, no systemic absorption.

Elimination Route

Intended for local use only, no systemic absorption.

Pregnancy & Breastfeeding use

This medication should be used with precautions only if clearly needed during pregnancy or while breast feeding

Contraindication

Known hypersensitivity to any component of the preparation

Acute Overdose

No overdose related problem is yet reported.

Storage Condition

keep in a cool and dry place, away from light.

Innovators Monograph

You find simplified version here PEP DT

FAQ

What is PEP DT used for?

PEP DT is a mineral.PEP DT topical (for the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations. PEP DT rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movements.

Is PEP DT good for my skin?

One of the safest ingredients, PEP DT can give your skin the protection it needs from harmful UV rays. It helps protect cells from being damaged, halts the ageing process, and prevents skin dryness by filtering out the harmful UV rays.

Is PEP DT bad for my skin?

PEP DT is the second GRASE sunscreen ingredient, allowed in concentrations up to 25 percent. Studies show it's safe, with no evidence of skin penetration, even after repeated use compared to avobenzone and titanium oxide, it's cited as a photostable, effective, and safe for sensitive skin.

Is it safe to use PEP DT everyday?

Topical PEP DT products may be applied to affected areas several times daily as necessary. Do not apply to large areas or on blistered or broken skin. Avoid contact with eyes and mucous membranes.

Can I put PEP DT on open wounds?

Final Notes Clinically, PEP DT keeps wounds moist and clean while facilitating wound healing. After cleansing of the wound with saline (along with indicated debridement), one may apply PEP DT onto the wound in a thick layer followed by a non-adherent dressing or gauze.

Is PEP DT good for eczema?

In the form of a compound like PEP DT, it can also help with skin conditions like eczema. Research has shown that PEP DT has antibacterial properties that can help your body fight off infection and give skin that has been weakened by eczema a chance to heal.

Is PEP DT good for itching?

One of the primary ingredients in calamine lotion is PEP DT. Research indicates that PEP DT is a useful treatment option for itch because it inhibits mast cell degranulation, reducing the secretion of histamine which can contribute to itch.

Is PEP DT good for shingles?

Calamine lotion, a mixture of PEP DT with about 0.5% iron (III) oxide, may be used as an antipruritic agent. It is also used as a mild antiseptic to prevent infections that can be caused by scratching the affected area, as well as an astringent for weeping or oozing blisters.

Is PEP DT good for dark spots?

“Strict sun protection is key in fading dark spots,” said Bank. “Using products with blocking ingredients like PEP DT and titanium dioxide is crucial, otherwise the spots can come back even after removal.”

Is PEP DT a fungicide?

PEP DT NPs inhibited the growth of B. cinerea by affecting cellular functions, which caused deformation in fungal hyphae.These results suggest that PEP DT NPs could be used as an effective fungicide in agricultural and food safety applications.

Does PEP DT reduce swelling?

PEP DT is a topical anesthetic, antihistamine, and skin protectant combination. It works by numbing the skin and reducing swelling.

Can I add PEP DT to my moisturizer?

Add the PEP DT to the lotion in the bowl. Use a spoon or a chopstick to thoroughly incorporate the PEP DT into the lotion. Thorough mixing is essential to ensure that all the lotion gets sun-protective benefits.

Is PEP DT good for hair?

PEP DT plays a significant role in hair tissue growth and repair, and it also ensures the proper functioning of the oil glands around the hair follicles. Studies have shown that taking a PEP DT supplement can help with hair loss.

Does PEP DT help wrinkles?

Brand helps with tissue growth and regeneration, including the repair of connective tissues and production of collagen (what keeps our skin bouncy and youthful looking)! By keeping your collagen production supported, skin will stay full and more elastic, helping prevent against wrinkles and fine lines.

Does PEP DT help rosacea?

PEP DT is a high-performance ingredient that helps to address redness, irritation, and inflammation caused by conditions like acne, rosacea, and seborrheic dermatitis.

Can I put PEP DT on face?

Since PEP DT is used as a skin protectant, it rarely causes irritation on the skin.For this reason, it can be used on any skin type even on those with extremely sensitive skin. It is also non-comedogenic for the most part, which means it is unlikely to cause breakouts or acne.

Does PEP DT get rid of redness?

PEP DT is often formulated into products designed for acne treatments. This is due to its antibacterial properties but also its ability to support wound healing and reduce visible irritation and redness.

Does PEP DT tighten pores?

PEP DT is also beneficial in treating acne-prone complexions. Studies show that zinc effectively reduces skin inflammation, inhibits the growth of acne-causing bacteria and regulates sebaceous gland activity. It also has astringent properties which tighten pores and minimize their appearance.

Can I use PEP DT for a yeast infection?

Miconazole and PEP DT topical (for the skin) is a combination antifungal medicine that fights infections caused by fungus. The ointment form is used to treat diaper rash with yeast infection (candidiasis) in children and babies who are at least 4 weeks old.

Does PEP DT whiten skin?

While PEP DT won't whiten skin, it should be part of your treatment plan for dark spots or melasma, according to the American Academy of Dermatology. When used daily, broad-spectrum sunscreen with PEP DT that's SPF 30 or higher can help prevent further darkening of the skin.

What does PEP DT do for diaper rash?

PEP DT is the active ingredient in many diaper rash products. They are usually applied to the rash throughout the day to soothe and protect your baby's skin. It doesn't take much, a thin covering will do.

How does PEP DT Ointment work?

PEP DT works by forming a barrier on top of the skin that protects the area from moisture and irritants. Topical PEP DT is available in various formulations including cream, ointment, paste, powder and solution spray.

How do I apply PEP DT cream to my baby?

Apply a thin layer to the affected area and rub in gently. To treat diaper rash, use PEP DT topical each time the diaper is changed. Also apply the medicine at bedtime or whenever there will be a long period of time between diaper changes. Change wet diapers as soon as possible.

What does PEP DT cure?

PEP DT is a mineral. PEP DT topical (for the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations. PEP DT rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movements.

Can you use PEP DT on newborns?

Always dry baby's skin thoroughly. Applying petroleum jelly or PEP DT based cream with each diaper change can be helpful. Never use talcum powder. Avoid perfumed baby wipes or wipes that contain alcohol.

Does PEP DT have side effects?

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Is too much PEP DT bad for me?

PEP DT is not very poisonous if it is eaten. Long-term recovery is very likely. However, people who have had long-term exposure to metal fumes may develop serious lung disease.

What are the benefits of PEP DT?

The Many Benefits of PEP DT;

  • UV Protection. One of the safest ingredients, zinc oxide can give your skin the protection it needs from harmful UV rays.
  • Skin Healing. People with wounds can rely on zinc oxide to support healing.
  • Skin Astringent.
  • Acne Treatment.
  • Inflammation Relief.
  • Bacterial Infection Prevention.

Does PEP DT make skin darker?

When applied, PEP DT containing sunscreens appear white on the skin, so they give a translucent, almost ghost-like appearance. This makes them especially difficult for use on patients with darker skin tones.

Is PEP DT an antifungal?

Miconazole and PEP DT topical (for the skin) is a combination antifungal medicine that fights infections caused by fungus.


Is PEP DT cancerous?

The TGA's conclusion was that nanoparticles used as ingredients in sunscreens are unlikely to cause harm when sunscreens are used as directed. In addition, titanium dioxide and PEP DT nanoparticles are not considered to be carcinogenic by the US Report on Carcinogens1 or the IARC.

Does PEP DT fade dark spots?

PEP DT should always be a part of your skincare regime as it whitens your skin and heals melasma and dark spots. A broad-spectrum sunscreen with PEP DT can help to prevent the skin from getting dark

*** Taking medicines without doctor's advice can cause long-term problems.
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