Peptavlon

Peptavlon Uses, Dosage, Side Effects, Food Interaction and all others data.

A synthetic pentapeptide that mimics the actions of endogenous gastrin when given parenterally. It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor. It has also been used as a diagnostic aid.

Peptavlon is indicated as a diagnostic aid for evaluation of gastric acid secretory function. It is effective in testing for anacidity (achlorhydria) in patients with suspected pernicious anemia, atrophic gastritis, or gastric carcinoma. It is also effective in determining the reduction in acid output after operations for peptic ulcer, such as vagotomy or gastric resection.

Trade Name Peptavlon
Availability Discontinued
Generic Pentagastrin
Pentagastrin Other Names Pentagastrin
Type
Formula C37H49N7O9S
Weight Average: 767.9
Monoisotopic: 767.33124736
Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Peptavlon
Peptavlon

Uses

Peptavlon is a gastrin-like molecule used as a diagnostic aid for the evaluation of gastric acid secretory function, gastric hypersecretion, and Zollinger-Ellison tumors.

Used as a diagnostic aid for evaluation of gastric acid secretory function

Peptavlon is also used to associated treatment for these conditions: C-cell hyperplasia, Medullary Thyroid Cancer (MTC)

How Peptavlon works

The exact mechanism by which pentagastrin stimulates gastric acid, pepsin, and intrinsic factor secretion is unknown; however, since pentagastrin is an analogue of natural gastrin, it is believed that it excites the oxyntic cells of the stomach to secrete to their maximum capacity. Peptavlon stimulates pancreatic secretion, especially when administered in large intramuscular doses. Peptavlon also increases gastrointestinal motility by a direct effect on the intestinal smooth muscle. However, it delays gastric emptying time probably by stimulation of terminal antral contractions, which enhance retropulsion.

Food Interaction

No interactions found.

Elimination Route

Rapidly absorbed after parenteral administration.

Half Life

10 minutes or less

Innovators Monograph

You find simplified version here Peptavlon

*** Taking medicines without doctor's advice can cause long-term problems.
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