Plitidepsine
Plitidepsine Uses, Dosage, Side Effects, Food Interaction and all others data.
Aplidine is a peptide found in tunicates which shows promise in shrinking tumors in pancreatic, stomach, bladder, and prostate cancers. The specific marine organism is Aplidium albicans. Aplidine is also of interest as a potential treatment for some leukemias.
| Trade Name | Plitidepsine |
| Generic | Plitidepsin |
| Plitidepsin Other Names | Dehydrodidemnin B, Plitidepsin, Plitidepsina, Plitidepsine, Plitidepsium |
| Type | |
| Formula | C57H87N7O15 |
| Weight | Average: 1110.357 Monoisotopic: 1109.626015129 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Intended for the treatment of various forms of cancer.
How Plitidepsine works
Aplidine inhibits the growth and induces apoptosis in MOLT-4 cells through the indirect inhibition of VEGF secretion which blocks the VEGF/VEGFR-1 autocrine loop necessary for the growth of these cells.
Innovators Monograph
You find simplified version here Plitidepsine
