Policarbofila
Policarbofila Uses, Dosage, Side Effects, Food Interaction and all others data.
Policarbofila calcium is a synthetic polymer manufactured from the cross-linking of polyacrylic acid with divinyl glycol and a calcium counter-ion.Policarbofila calcium is a stool stabilizer used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea.Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps. It is insoluble in water, dilute acids, and dilute alkali. The material possesses exceptionally high water-binding capacity. is not absorbed, does not interfere with the activity of digestive enzymes or intestinal absorption, possesses satisfactory stability, is physiologically inert, and does not cause gastrointestinal irritation.
Relieves constipation or diarrhea associated with bowel disorders and acute nonspecific diarrhea.
Trade Name | Policarbofila |
Availability | Over the counter |
Generic | Polycarbophil |
Polycarbophil Other Names | Policarbofila, Polycarbofil, Polycarbophil, Polycarbophile, Polycarbophilum |
Related Drugs | MiraLAX, Colace, docusate, Linzess, bisacodyl, senna |
Type | |
Protein binding | Calcium polycarbophil is not absorbed from the intestine. |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Policarbofila is used to treat constipation and to help maintain regular bowel movements.
How Policarbofila works
It is known as a bulk-forming laxative. It increases the bulk in the stool, an effect that helps to cause movement of the intestines. It also works by increasing the amount of water in the stool, making the stool softer and easier to pass.
Toxicity
The LD50 of calcium polycarbophil in young adult rats approximated 20 g/kg.
Food Interaction
[Moderate] ADJUST DOSING INTERVAL: Bulk-forming laxatives such as guar gum, psyllium, polycarbophil, or methylcellulose may affect the bioavailability of concomitantly administered substances due to their effect on the rate of gastrointestinal transit and gastric emptying.
MANAGEMENT: In general, oral medications should be administered at least 2 hours before or 2 hours after dosing of the bulk-forming laxative.
Policarbofila Drug Interaction
Unknown: diphenhydramine, diphenhydramine, calcium / vitamin d, calcium / vitamin d, omega-3 polyunsaturated fatty acids, omega-3 polyunsaturated fatty acids, atorvastatin, atorvastatin, metoprolol, metoprolol, bifidobacterium infantis / lactobacillus acidophilus, bifidobacterium infantis / lactobacillus acidophilus, acetaminophen, acetaminophen, cyanocobalamin, cyanocobalamin, ascorbic acid, ascorbic acid, cholecalciferol, cholecalciferol
Policarbofila Disease Interaction
Major: intestinal obstruction, inflammatory bowel disease, intestinal obstruction disordersModerate: renal dysfunction, hypercalcemia
Volume of Distribution
Calcium polycarbophil is not absorbed from the intestine.
Elimination Route
Calcium polycarbophil is not absorbed from the intestine.
Half Life
Calcium polycarbophil is not absorbed from the intestine.
Clearance
Calcium polycarbophil is not absorbed from the intestine.
Elimination Route
Excreted in feces.
Innovators Monograph
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