Polimod Oral Uses, Dosage, Side Effects and more

Polimod Oral is a synthetic dipeptide with immunomodulatory properties.

Polimod Oral modulates the immune system to induce an immune response against bacterial or viral pathogens

Trade Name	Polimod Oral
Generic	Pidotimod
Pidotimod Other Names	Pidotimod
Weight	400mg
Type	Liquid
Formula	C₉H₁₂N₂O₄S
Weight	Average: 244.27 Monoisotopic: 244.051778048
Groups	Experimental
Therapeutic Class
Manufacturer	Ajanta Pharma Ltd
Available Country	India
Last Updated:	January 7, 2025 at 1:49 am

Uses

Polimod Oral is a synthetic agent with immunomodulatory properties used in patients with documented cell-mediated immunosuppression to stimulate their immunity during lung and urinary tract infections.

For use as immunostimulant therapy for treatment of cell-mediated immunosuppression with respiratory or urinary infections .

Polimod Oral is also used to associated treatment for these conditions: Recurrent Upper Respiratory Tract Infection, Immunostimulation

How Polimod Oral works

Polimod Oral inhibits tumor necrosis factor α (TNF-α) induced increases in extracellular signal-related kinase (ERK) phosphorylation . It also increases nuclear factor κB (NFκB) expression and translocation to the nucleus. It is these to modulatory effects on ERK and NFκB signalling which are thought to produce the increase in toll-like receptor expression seen with pidotimod. Polimod Oral increase maturation of dendritic cells responsible for presenting antigens to naive Th-cells . It also appears to result in a greater population these cells diiferentiating to Th1 cells which are believed to mediate the immune response to pathogens like bacteria and viruses . Lastly, pidotimod appears to increase antigen-specific antibody titer and cytotoxic response with antigen exposure . The precise mechanism and timeline of events leading to these effects is unknown.